Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mefenamic acid
Drug ID BADD_D01368
Description A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Indications and Usage For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Marketing Status Prescription
ATC Code M01AG01
DrugBank ID DB00784
KEGG ID D00151
MeSH ID D008528
PubChem ID 4044
TTD Drug ID D05FTJ
NDC Product Code 49452-4398; 0276-0509; 52935-0008; 51927-4457; 51552-1367; 58747-0601; 42571-258; 62350-0015; 68180-185; 38779-0669; 62250-677; 22365-117
Synonyms Mefenamic Acid | Acid, Mefenamic | Mefenaminic Acid | Pontal | Contraflam | Coslan | Parkemed | Ponstan Forte | Ponsyl | Dysman | Mefac | Mefacit | Nu-Mefenamic | Nu Mefenamic | Pinalgesic | PMS-Mefenamic Acid | PMS Mefenamic Acid | Ponalar | Ponalgic | Ponmel | Ponstan | Ponstel | Mefic | Apo-Mefenamic | Apo Mefenamic
Chemical Information
Molecular Formula C15H15NO2
CAS Registry Number 61-68-7
SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dry mouth07.06.01.002--
Duodenal ulcer07.04.02.002--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Ear disorder04.03.01.001--Not Available
Ear pain04.03.01.003--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Enterocolitis07.08.03.003--
Eosinophilia01.02.04.001--
Eructation07.01.02.003--
Erythema multiforme10.01.03.015; 23.03.01.003--
Eye irritation06.04.05.003--Not Available
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gastric ulcer07.04.03.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.009--Not Available
Gastrointestinal pain07.01.05.005--
Gastrointestinal perforation07.04.04.001--Not Available
Glomerulonephritis20.05.01.001; 10.02.01.006--Not Available
Glossitis07.14.01.001--Not Available
Glucose tolerance impaired14.06.02.001; 05.06.02.001--
Haematemesis24.07.02.011; 07.12.02.002--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
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