Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mafenide
Drug ID BADD_D01337
Description Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Indications and Usage Mafenide is indicated in the treatment of severe burns.
Marketing Status Prescription
ATC Code D06BA03
DrugBank ID DB06795
KEGG ID D02351
MeSH ID D008272
PubChem ID 3998
TTD Drug ID D0K1QD
NDC Product Code Not Available
Synonyms Mafenide | Maphenid | Mafenide Acetate | Sulfamylon | Marfanil | Napaltan | 4-Homosulfanilamide | 4 Homosulfanilamide | Sulfabenzamine | Bensulfamide | Mafylon
Chemical Information
Molecular Formula C7H10N2O2S
CAS Registry Number 138-39-6
SMILES C1=CC(=CC=C1CN)S(=O)(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Blister23.03.01.001; 12.01.06.002--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Face oedema08.01.07.003; 23.04.01.004; 10.01.05.002--
Glucose-6-phosphate dehydrogenase deficiency14.14.03.001; 03.08.03.001; 01.06.05.001--Not Available
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Hyperventilation19.01.02.004; 22.02.01.006--Not Available
Metabolic acidosis14.01.01.003--Not Available
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
PCO213.02.01.017--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Swelling08.01.03.015--Not Available
Tachypnoea22.02.01.014--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Skin maceration23.03.03.016--Not Available
Excoriation23.03.11.003; 12.01.06.007--Not Available
Haemorrhage24.07.01.002--Not Available
Porphyrin metabolism disorder14.14.01.006; 09.01.10.004; 03.08.01.006--Not Available
Bone marrow failure01.03.03.005--
Accidental exposure to product12.06.02.002--Not Available
The 1th Page    1    Total 1 Pages