Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status Prescription
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Salivary hypersecretion07.06.01.0090.001592%Not Available
Schizoaffective disorder19.03.02.0020.001592%Not Available
Schizophrenia19.03.04.0010.003981%Not Available
Sedation17.02.04.0050.007962%Not Available
Seizure17.12.03.0010.006370%
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Sleep disorder19.02.04.001--Not Available
Somnolence19.02.05.003; 17.02.04.0060.005574%
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.0030.001592%Not Available
Sudden death08.04.01.003; 02.03.04.0130.000415%
Suicidal ideation19.12.01.0030.008759%
Suicide attempt19.12.01.0040.007166%
Swelling face10.01.05.018; 23.04.01.0180.004777%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.007166%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.003185%
Tachycardia02.03.02.007--Not Available
Tardive dyskinesia17.01.02.0120.011944%Not Available
Thinking abnormal19.10.03.001; 17.02.05.0230.001592%Not Available
Throat tightness22.02.05.015; 19.01.02.005--Not Available
Thrombocytopenia01.08.01.0020.003185%Not Available
Tongue spasm07.14.02.008--Not Available
Torsade de pointes02.03.04.005--Not Available
Torticollis17.01.03.003; 15.05.04.003--Not Available
Transient ischaemic attack17.08.04.001; 24.04.06.0050.003185%
Tremor17.01.06.0020.008759%
Trismus17.01.03.004; 15.05.04.004--
Tuberculosis11.04.01.0060.001592%Not Available
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
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