Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Rash23.03.13.001--Not Available
Rash pruritic23.03.13.0300.001443%Not Available
Renal failure20.01.03.005--Not Available
Respiratory distress22.02.01.0120.000492%Not Available
Restlessness19.11.02.002; 17.02.05.0210.007017%
Retching07.01.07.0020.001115%Not Available
Rhabdomyolysis15.05.05.0020.000820%
Salivary hypersecretion07.06.01.0090.000885%Not Available
Schizoaffective disorder19.03.02.0020.000328%Not Available
Schizophrenia19.03.04.0010.003509%Not Available
Screaming19.04.02.020; 08.01.03.0990.001279%Not Available
Sedation17.02.04.0050.007345%Not Available
Seizure17.12.03.001--
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.0410.000492%Not Available
Sexual dysfunction21.03.02.003; 19.08.05.0020.001213%Not Available
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Sleep disorder19.02.04.0010.002000%Not Available
Somnolence19.02.05.003; 17.02.04.0060.012363%
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.0030.000492%Not Available
Sudden death02.03.04.013; 08.04.01.0030.000328%
Suicidal ideation19.12.01.0030.004919%
Suicide attempt19.12.01.0040.002295%
Swelling face08.01.03.100; 23.04.01.018; 10.01.05.0180.002951%Not Available
Swollen tongue07.14.02.003; 23.04.01.014; 10.01.05.0150.004591%Not Available
Syncope24.06.02.012; 02.11.04.015; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Tardive dyskinesia17.01.02.0120.011379%Not Available
Therapeutic response unexpected08.06.01.0010.002886%Not Available
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