Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Loxapine
Drug ID BADD_D01326
Description An antipsychotic agent used in schizophrenia. [PubChem]
Indications and Usage For the management of the manifestations of psychotic disorders such as schizophrenia
Marketing Status Prescription; Discontinued
ATC Code N05AH01
DrugBank ID DB00408
KEGG ID D02340
MeSH ID D008152
PubChem ID 3964
TTD Drug ID D0U5OE
NDC Product Code 0527-1395; 64850-891; 70518-1896; 0527-1397; 35573-438; 0591-0371; 70518-0346; 70518-2120; 0527-1396; 35573-437; 0527-1394; 64850-893; 0591-0372; 0591-0369; 70518-0416; 35573-436; 0591-0370; 64850-890; 64850-892; 70518-1681; 53296-0095; 50090-4701; 70518-0283; 35573-439; 70518-0347
Synonyms Loxapine | 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine | Oxilapine | Cloxazepine | Loxapine Hydrochloride | Hydrochloride, Loxapine | Loxitane | Loxapine Succinate | Succinate, Loxapine | Loxapinsuccinate | Loxipine Succinate | Loxipine Maleate | Maleate, Loxipine | CL-71,563 | CL 71,563 | CL71,563 | Loxapine Monohydrochloride
Chemical Information
Molecular Formula C18H18ClN3O
CAS Registry Number 1977-10-2
SMILES CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angiopathy24.03.02.007--Not Available
Electrocardiogram change13.14.05.014--Not Available
Mediastinal disorder22.09.03.001--Not Available
Psychotic disorder19.03.01.002--
Pulmonary function test decreased13.19.01.001--Not Available
Liver injury12.01.02.003; 09.01.07.022--Not Available
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