Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lormetazepam
Drug ID BADD_D01321
Description Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Indications and Usage For the treatment of short-term insomnia [L927]
Marketing Status Not Available
ATC Code N05CD06
DrugBank ID DB13872
KEGG ID D01657
MeSH ID C023842
PubChem ID 13314
TTD Drug ID D0I8HJ
NDC Product Code 12828-0021
Synonyms lormetazepam | methyllorazepam
Chemical Information
Molecular Formula C16H12Cl2N2O2
CAS Registry Number 848-75-9
SMILES CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O)C3=CC=CC=C3Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperacusis17.04.03.003; 04.02.02.001--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Irritability19.04.02.013; 08.01.03.011--
Libido decreased21.03.02.005; 19.08.03.001--
Micturition disorder20.02.02.005--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Nightmare19.02.03.003--Not Available
Paraesthesia17.02.06.005--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder19.19.02.002; 17.02.08.003; 22.02.05.034--Not Available
Suicide attempt19.12.01.004--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Visual impairment06.02.06.008--Not Available
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