Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lormetazepam
Drug ID BADD_D01321
Description Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Indications and Usage For the treatment of short-term insomnia [L927]
Marketing Status Not Available
ATC Code N05CD06
DrugBank ID DB13872
KEGG ID D01657
MeSH ID C023842
PubChem ID 13314
TTD Drug ID D0I8HJ
NDC Product Code 12828-0021
Synonyms lormetazepam | methyllorazepam
Chemical Information
Molecular Formula C16H12Cl2N2O2
CAS Registry Number 848-75-9
SMILES CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O)C3=CC=CC=C3Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Acute psychosis19.03.01.001--Not Available
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Altered state of consciousness17.02.04.001; 19.07.01.003--Not Available
Amnesia19.20.01.001; 17.03.02.001--
Anger19.04.02.001--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anterograde amnesia19.20.01.005; 17.03.02.005--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Completed suicide19.12.01.001; 08.04.01.010--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Delusion19.10.01.001--
Dependence19.07.02.003--Not Available
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Derealisation19.10.02.001--Not Available
Dermatitis23.03.04.002--Not Available
Diplopia06.02.06.002; 17.17.01.005--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug dependence19.07.02.009--Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.004--Not Available
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Emotional disorder19.04.02.005--Not Available
Epilepsy17.12.03.002--Not Available
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