| Drug Name |
Lorazepam |
| Drug ID |
BADD_D01318 |
| Description |
Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.[A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.[L5095] |
| Indications and Usage |
Lorazepam is FDA-approved for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used as an anesthesia premedication in adults to relieve anxiety or to produce sedation/amnesia and for the treatment of status epilepticus.[T385]
Some off-label indications of lorazepam include rapid tranquilization of an agitated patient, alcohol withdrawal delirium, alcohol withdrawal syndrome, muscle spasms, insomnia, panic disorder, delirium, chemotherapy-associated anticipatory nausea and vomiting, and psychogenic catatonia.[T385] |
| Marketing Status |
approved |
| ATC Code |
N05BA06 |
| DrugBank ID |
DB00186
|
| KEGG ID |
D00365
|
| MeSH ID |
D008140
|
| PubChem ID |
3958
|
| TTD Drug ID |
D0E0OG
|
| NDC Product Code |
0641-6047; 0641-6049; 0904-6008; 71554-009; 72166-001; 0093-3426; 0121-0770; 52427-663; 55154-7976; 60687-638; 65162-018; 68788-7533; 69315-904; 70518-0275; 70518-0445; 0641-6002; 0641-6048; 72789-236; 76329-8261; 0904-6007; 51927-0195; 67763-101; 76420-296; 0093-3427; 52427-661; 61919-062; 63187-536; 67296-1478; 67296-1622; 68071-5022; 0409-6778; 71205-235; 71335-1467; 71610-600; 72572-380; 0641-6000; 0641-6001; 0641-6003; 0641-6051; 48087-0076; 51927-1005; 55154-7975; 61919-607; 67296-1332; 67544-142; 71610-008; 71610-654; 71610-655; 58118-1095; 63304-773; 65162-687; 68071-4916; 68071-5250; 70518-0486; 70518-2186; 70518-2442; 71205-228; 71335-0329; 71335-1455; 71335-1694; 0641-6207; 57218-950; 0187-0064; 53002-5291; 58118-0904; 60760-516; 63187-576; 68071-2666; 70934-782; 72789-197; 72789-226; 0904-6009; 13107-085; 0187-0065; 50383-705; 54348-049; 60687-627; 60687-649; 63304-774; 65162-015; 71335-1138; 71610-255; 12828-0025; 0093-3425; 53002-6290; 67544-191; 68071-3096; 0409-1985; 68788-7355; 70518-1275; 70518-3188; 70518-3423; 71205-166; 71205-756; 71610-122; 71610-229; 71610-674; 0641-6044; 0641-6046; 0641-6050; 64330-020; 43353-255; 52427-658; 55154-7977; 63304-772; 68788-7428; 69315-906; 70518-2268; 70518-3225; 72189-351; 17478-040; 52427-667; 55700-778; 65162-017; 67544-261; 70518-1520; 0054-3532; 71335-0655; 49452-4140; 51552-0729; 13107-083; 50090-5508; 63629-2953; 68071-2662; 68071-3121; 68071-5068; 69315-905; 71610-178; 71610-199; 71610-225; 0641-6045; 52696-0002; 62991-1682; 13107-084; 45865-499; 0187-0063; 50090-5509; 58118-1096 |
| UNII |
O26FZP769L
|
| Synonyms |
Lorazepam | Ativan | Orfidal Wyeth | Wyeth, Orfidal | Témesta | Tolid | Donix | Duralozam | Durazolam | Idalprem | Laubeel | Lorazep Von Ct | Von Ct, Lorazep | Lorazepam Medical | Medical, Lorazepam | Lorazepam-Neuraxpharm | Lorazepam Neuraxpharm | Lorazepam-Ratiopharm | Lorazepam Ratiopharm | Novo-Lorazem | Novo Lorazem | Nu-Loraz | Nu Loraz | Sedicepan | Sinestron | WY-4036 | WY 4036 | WY4036 | Apo-Lorazepam | Apo Lorazepam | Somagerol | Temesta |
