Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levalbuterol hydrochloride
Drug ID BADD_D01263
Description Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol (levalbuterol).
Indications and Usage Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB13139
KEGG ID D02281
MeSH ID D064412
PubChem ID 123601
TTD Drug ID D02ZJI
NDC Product Code 0115-9931; 66993-021; 76204-800; 17478-174; 17337-0524; 17478-172; 17478-171; 35573-445; 0115-9930; 0115-9932; 76204-700; 35573-443; 53104-7719; 51927-5157; 66993-022; 76204-900; 66993-023; 48954-719; 17478-173; 35573-444; 68071-5027; 15308-0310
Synonyms Levalbuterol | Xopenex | Levalbuterol Hydrochloride | Hydrochloride, Levalbuterol | Levosalbutamol Hydrochloride | Hydrochloride, Levosalbutamol
Chemical Information
Molecular Formula C13H22ClNO3
CAS Registry Number 50293-90-8
SMILES CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Chills15.05.03.016; 08.01.09.001--
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dry throat22.02.05.004; 07.06.01.005--Not Available
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Eczema23.03.04.006--
Electrocardiogram abnormal13.14.05.001--Not Available
Extrasystoles02.03.02.003--Not Available
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypoaesthesia17.02.06.023--Not Available
Hypotension24.06.03.002--
Influenza22.07.02.001; 11.05.03.001--Not Available
Injury12.01.08.004--Not Available
Insomnia17.15.03.002; 19.02.01.002--
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