Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Ketoprofen
Drug ID BADD_D01231
Description Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Indications and Usage For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
Marketing Status approved; vet_approved
ATC Code M01AE03; M02AA10
DrugBank ID DB01009
KEGG ID D00132
MeSH ID D007660
PubChem ID 3825
TTD Drug ID D0W9WF
NDC Product Code 51604-0011; 71574-122; 0276-0506; 43235-0010; 51927-0304; 76465-0001; 12660-0006; 38779-3039; 49452-3924; 51927-0231; 45865-485; 0276-0504; 51927-0025; 51927-0057; 68981-031; 63275-9996; 82348-102; 63187-018; 38779-0078; 0378-8200; 51552-0307; 51927-0299; 79572-019
UNII 90Y4QC304K
Synonyms Ketoprofen | Benzoylhydratropic Acid | 2-(3-Benzoylphenyl)propionic Acid | Profenid | Alrheumum | Orudis | 19,583 RP | RP, 19,583 | RP-19583 | RP 19583 | RP19583 | Alrheumat
Chemical Information
Molecular Formula C16H14O3
CAS Registry Number 22071-15-4
SMILES CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pulmonary infarction24.04.09.001; 22.06.02.0020.002240%Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.0010.016131%Not Available
Rash erythematous23.03.13.0290.003361%Not Available
Rash maculo-papular23.03.13.0040.003361%
Rash pruritic23.03.13.0300.002240%Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.0010.006721%
Renal failure20.01.03.0050.003361%Not Available
Renal infarct20.01.07.008; 24.01.11.0040.002240%Not Available
Renal tubular disorder20.05.03.004--Not Available
Respiratory disorder22.02.07.0020.004481%Not Available
Respiratory distress22.02.01.0120.002240%Not Available
Retching07.01.07.0020.002240%Not Available
Retinal haemorrhage24.07.05.003; 06.10.01.001--Not Available
Rhabdomyolysis15.05.05.0020.002240%
Rhinitis22.07.03.006; 11.01.13.004--
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Sepsis11.01.11.003--
Shock24.06.02.0020.002240%Not Available
Sjogren's syndrome15.06.01.015; 10.04.04.009; 07.06.01.010; 06.08.02.011--Not Available
Skin discolouration23.03.03.005--Not Available
Skin reaction23.03.03.013; 10.01.03.0190.002240%Not Available
Somnolence19.02.05.003; 17.02.04.0060.007841%
Splenic infarction24.04.08.024; 01.09.02.0040.002240%Not Available
Stevens-Johnson syndrome12.03.01.014; 11.07.01.005; 10.01.01.045; 23.03.01.007--
Stomatitis07.05.06.005--
Stomatitis necrotising07.05.06.006--Not Available
Suicide attempt19.12.01.0040.020163%
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ADReCS-Target
Drug Name ADR Term Target
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