Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Isoflurane
Drug ID BADD_D01203
Description A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Indications and Usage For induction and maintenance of general anesthesia.
Marketing Status Prescription; Discontinued
ATC Code N01AB06
DrugBank ID DB00753
KEGG ID D00545
MeSH ID D007530
PubChem ID 3763
TTD Drug ID D0DP6L
NDC Product Code 12164-002; 42677-114; 66794-020; 65085-0019; 66794-017; 12164-012; 66794-019; 10019-360; 66794-011
Synonyms Isoflurane
Chemical Information
Molecular Formula C3H2ClF5O
CAS Registry Number 26675-46-7
SMILES C(C(F)(F)F)(OC(F)F)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Cognitive disorderOccludinQ6P6T5Not AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Arrhythmia02.03.02.001--Not Available
Body temperature increased13.15.01.001--Not Available
Breath holding19.01.01.002; 22.02.01.016--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Carbon dioxide increased13.02.01.011--Not Available
Cardiac arrest02.03.04.001--
Chills15.05.03.016; 08.01.09.001--
Cough22.02.03.001--
Delirium19.13.02.001--
Dermatitis23.03.04.002--Not Available
Hallucination19.10.02.002--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001--Not Available
Hepatic necrosis09.01.07.002--
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hiccups22.02.04.002; 07.01.06.009--
Hypercapnia22.02.02.002; 14.01.04.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperkalaemia14.05.03.001--
Hypotension24.06.03.002--
Ileus07.13.01.001--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Laryngospasm22.04.02.002--
Muscle rigidity15.05.04.001; 17.05.02.005--Not Available
Nausea07.01.07.001--
Necrosis24.04.02.006; 08.03.03.001--Not Available
Rash23.03.13.001--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
The 1th Page    1 2    Next   Last    Total 2 Pages