Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ioxilan
Drug ID BADD_D01189
Description Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Indications and Usage When administered intravenously, Ioxilan is indicated for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body (300 and 350 mgI/mL).
Marketing Status Discontinued
ATC Code V08AB12
DrugBank ID DB09135
KEGG ID D02161
MeSH ID C055357
PubChem ID 3743
TTD Drug ID D02BLO
NDC Product Code Not Available
Synonyms ioxilan | 5-(N-2,3-dihydroxypropylacetamido)-2,4,6-triiodo-N-(2-hydroxyethyl)-N'-(2,3-dihydroxypropyl)isophthalamide | Oxilan
Chemical Information
Molecular Formula C18H24I3N3O8
CAS Registry Number 107793-72-6
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCCO)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Amblyopia06.02.01.001--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Anuria20.01.03.002--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Chills15.05.03.016; 08.01.09.001--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.004--
Feeling hot08.01.09.009--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Haematoma24.07.01.001--
Haematuria24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
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