Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ioversol
Drug ID BADD_D01186
Description Ioversol is classified as an _organoiodine_ compound and is used as a contrast dye in diagnostic procedures. It contains high levels of iodine in addition to various hydrophilic groups.
Indications and Usage Optiray 350 is indicated in adults for peripheral and coronary arteriography and left ventriculography. Optiray 350 is also indicated for contrast enhanced computed tomographic imaging of the head and body, intravenous excretory urography, intravenous digital subtraction angiography and venography. Optiray 350 is indicated in children for angiocardiography. Optiray 320 is indicated in adults for angiography throughout the cardiovascular system. The uses include cerebral, coronary, peripheral, visceral and renal arteriography, venography, aortography, and left ventriculography. Optiray 320 is also indicated for contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 320 is indicated in children for angiocardiography, contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 300 is indicated for cerebral angiography and peripheral arteriography. Optiray 300 is also indicated for contrast enhanced computed tomographic imaging of the head and body, venography, and intravenous excretory urography. Optiray 240 is indicated for cerebral angiography and venography. Optiray 240 is also indicated for contrast enhanced computed tomographic imaging of the head and body and intravenous excretory urography.
Marketing Status approved
ATC Code V08AB07
DrugBank ID DB09134
KEGG ID D01555
MeSH ID C054871
PubChem ID 3741
TTD Drug ID D0U1ZD
NDC Product Code 0019-1323; 0019-1332; 0406-7888; 0019-1333; 57884-0015; 67684-8777
UNII N3RIB7X24K
Synonyms ioversol | Optiray 320 | Optiray | Optiray 300
Chemical Information
Molecular Formula C18H24I3N3O9
CAS Registry Number 87771-40-2
SMILES C(CO)N(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)CO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dehydration14.05.05.001--
Depressed level of consciousness17.02.04.0020.014227%
Dermatitis23.03.04.002--Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.017783%Not Available
Dermatitis bullous23.03.01.0020.007113%
Dermatitis exfoliative23.03.07.001; 10.01.01.0040.007113%
Diarrhoea07.02.01.001--
Diplegia17.01.04.015--Not Available
Discomfort08.01.08.003--Not Available
Disorientation19.13.01.002; 17.02.05.0150.007113%Not Available
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.0070.121639%
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.021340%Not Available
Dry mouth07.06.01.0020.022763%
Dry throat22.12.03.005; 07.06.01.0050.022763%Not Available
Dysgeusia17.02.07.003; 07.14.03.001--
Dysphagia07.01.06.0030.132309%
Dysphonia22.12.03.006; 17.02.08.004; 19.19.03.0020.113814%
Dyspnoea02.11.05.003; 22.02.01.0040.629535%
Dyspnoea exertional02.11.05.005; 22.02.01.0050.007113%Not Available
Ear swelling04.03.01.0140.015649%Not Available
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Electrocardiogram ST segment depression13.14.05.005--Not Available
Electrocardiogram ST segment elevation13.14.05.025--Not Available
Embolic stroke17.08.01.032; 24.01.04.0100.007113%Not Available
Eosinophilia01.02.04.0010.010670%
Epilepsy17.12.03.002--Not Available
Erythema23.03.06.0010.435339%Not Available
Erythema of eyelid06.04.04.003; 23.03.06.0060.007113%Not Available
Extravasation08.01.03.0080.070423%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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