Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iotrolan
Drug ID BADD_D01185
Description Nonionic, isotonic contrast medium designed for intrathecal use.
Indications and Usage
Marketing Status Discontinued
ATC Code V08AB06
DrugBank ID DB09487
KEGG ID D01714
MeSH ID C033300
PubChem ID 3738
TTD Drug ID D0B8LN
NDC Product Code Not Available
Synonyms iotrolan | iotrol | Isovist | Isovist 300 | Osmovist | DL 3-117 | DL 3117 | DL-3-117
Chemical Information
Molecular Formula C37H48I6N6O18
CAS Registry Number 79770-24-4
SMILES CN(C1=C(C(=C(C(=C1I)C(=O)NC(CO)C(CO)O)I)C(=O)NC(CO)C(CO)O)I)C(=O)CC(=O)N(C)C2=C( C(=C(C(=C2I)C(=O)NC(CO)C(CO)O)I)C(=O)NC(CO)C(CO)O)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema23.03.06.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Feeling cold08.01.09.008--Not Available
Feeling hot08.01.09.009--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Haemoglobin13.01.05.018--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypotension24.06.03.002--
Lacrimation increased06.08.02.004--
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Laryngospasm22.04.02.002--
Meningitis aseptic17.06.03.002; 11.01.03.002--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nystagmus06.05.02.006; 17.02.02.006--
Pain08.01.08.004--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Paraesthesia17.02.06.005--
Renal failure20.01.03.005--Not Available
Retrograde amnesia17.03.02.006; 19.20.01.006--Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
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