ADReCS

Pharmaceutical Information

Drug Name	Iohexol
Drug ID	BADD_D01180
Description	Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage	Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status	approved
ATC Code	V08AB02
DrugBank ID	DB01362
KEGG ID	D01817
MeSH ID	D007472
PubChem ID	3730
TTD Drug ID	D02BLO
NDC Product Code	43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII	4419T9MX03
Synonyms	Iohexol \| Iohexol 350 \| Nycodenz \| Compound 545 \| Exypaque \| Omnipaque

Chemical Information

Molecular Formula	C19H26I3N3O9
CAS Registry Number	66108-95-0
SMILES	CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Petechiae	24.07.06.004; 23.06.01.003; 01.01.03.002	0.032010%		Not Available
Pharyngeal oedema	23.04.01.016; 22.04.05.003; 10.01.05.016	0.179257%		Not Available
Phlebitis	24.12.03.004; 12.02.01.002	0.007113%
Photophobia	17.17.02.006; 06.01.01.004	-	-
Pneumothorax	22.05.02.003	0.039124%
Posture abnormal	15.03.05.029; 17.02.05.033	0.007113%		Not Available
Presyncope	02.11.04.013; 24.06.02.010; 17.02.05.009	0.041969%
Productive cough	22.02.03.005	0.014227%
Pruritus	23.03.12.001	3.294921%
Pulmonary oedema	22.01.03.003; 02.05.02.003	0.035567%
Pyrexia	08.05.02.003	0.315834%
Quadriplegia	17.01.04.013	-	-	Not Available
Radiculopathy	17.10.01.005	-	-
Rales	22.12.01.011	0.007113%		Not Available
Rash	23.03.13.001	0.899132%		Not Available
Rash erythematous	23.03.13.029	0.153649%		Not Available
Rash macular	23.03.13.003	0.059752%		Not Available
Rash maculo-papular	23.03.13.004	0.067577%
Rash papular	23.03.13.017	0.017783%		Not Available
Rash pruritic	23.03.13.030	0.100299%		Not Available
Rash vesicular	23.03.13.009	0.010670%		Not Available
Renal failure	20.01.03.005	-	-	Not Available
Renal tubular necrosis	20.01.07.003	0.035567%		Not Available
Respiration abnormal	22.02.01.041	0.007113%		Not Available
Respiratory arrest	22.02.01.009	0.071134%		Not Available
Respiratory disorder	22.02.07.002	0.088917%		Not Available
Respiratory distress	22.02.01.012	0.125907%		Not Available
Restlessness	19.11.02.002; 17.02.05.021	-	-
Retching	07.01.07.002	0.045526%		Not Available
Rhinitis allergic	22.04.04.003; 10.01.04.003	0.007113%

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