Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Interferon alfa-2b
Drug ID BADD_D01167
Description Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Indications and Usage For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.
Marketing Status Prescription
ATC Code L03AB05
DrugBank ID DB00105
KEGG ID D02745
MeSH ID D000077190
PubChem ID 71306834
TTD Drug ID D0P0WV
NDC Product Code 0085-4350; 0085-4352; 53713-0080; 0085-1133; 53713-0082; 53713-0079; 0085-4351; 53713-0078; 0085-1168; 53713-0081
Synonyms Interferon alpha-2 | Interferon alpha 2 | Interferon-alpha 2 | Interferon alpha-A | Interferon alpha A | LeIF A | IFN-alpha 2 | IFN-alpha-2 | Interferon alfa-2a | Interferon alfa 2a | Recombinant Interferon alpha-2a | Interferon alpha-2a, Recombinant | Recombinant Interferon alpha 2a | Roferon-A | Roferon A | RoferonA | Ro 22-8181 | Ro 22 8181 | Ro 228181 | Viferon | Sch-30500 | Sch 30500 | Sch30500 | Intron A (Interferon) | Reaferon | Interferon alfa-2b | Interferon alfa 2b | Interferon alpha-2b, Recombinant | Interferon alpha 2b, Recombinant | Recombinant Interferon alpha-2b | Recombinant Interferon alpha 2b | IFNalpha-2b, Recombinant | IFNalpha 2b, Recombinant | Recombinant IFNalpha-2b
Chemical Information
Molecular Formula C16H17Cl3I2N3NaO5S
CAS Registry Number 98530-12-2
SMILES CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N2C=CN=C2.C(S(=O)(=O)[O-])(I)I.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
Ear disorder04.03.01.001--Not Available
Ear pain04.03.01.003--
Eczema23.03.04.006--
Emphysema22.01.02.002--Not Available
Encephalopathy17.13.02.001--
Endocrine disorder05.09.01.001--Not Available
Enuresis20.02.02.003; 19.07.04.001--Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Eructation07.01.02.003--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Extrapyramidal disorder17.01.02.007--
Extrasystoles02.03.02.003--Not Available
Eye disorder06.08.03.001--Not Available
Eye pain06.08.03.002--
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Facial paralysis17.04.03.008--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling drunk08.01.09.015--Not Available
Flat affect19.04.01.004--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Folliculitis11.01.12.018; 23.09.04.007--
Fungal infection11.03.05.001--Not Available
Furuncle23.09.01.004; 11.02.05.008--Not Available
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