Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Interferon alfa-2a
Drug ID BADD_D01166
Description Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.
Indications and Usage For the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi's sarcoma, and chronic myelogenous leukemia. Also for the treatment of oral warts arising from HIV infection.
Marketing Status approved; investigational
ATC Code L03AB04
DrugBank ID DB00034
KEGG ID D00745
MeSH ID D000077190
PubChem ID Not Available
TTD Drug ID D0P0WV
NDC Product Code Not Available
UNII 47RRR83SK7
Synonyms Interferon alpha-2 | Interferon alpha 2 | Interferon-alpha 2 | Interferon alpha-A | Interferon alpha A | LeIF A | IFN-alpha 2 | IFN-alpha-2 | Interferon alfa-2a | Interferon alfa 2a | Recombinant Interferon alpha-2a | Interferon alpha-2a, Recombinant | Recombinant Interferon alpha 2a | Roferon-A | Roferon A | RoferonA | Ro 22-8181 | Ro 22 8181 | Ro 228181 | Viferon | Sch-30500 | Sch 30500 | Sch30500 | Intron A (Interferon) | Reaferon | Interferon alfa-2b | Interferon alfa 2b | Interferon alpha-2b, Recombinant | Interferon alpha 2b, Recombinant | Recombinant Interferon alpha-2b | Recombinant Interferon alpha 2b | IFNalpha-2b, Recombinant | IFNalpha 2b, Recombinant | Recombinant IFNalpha-2b
Chemical Information
Molecular Formula Not Available
CAS Registry Number 76543-88-9
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.001--
Cyanosis24.03.01.007; 22.02.02.007; 23.06.04.005; 02.11.04.004--
Deafness04.02.01.001--Not Available
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry skin23.03.03.001--
Dry throat22.12.03.005; 07.06.01.005--Not Available
Dysarthria19.19.03.001; 17.02.08.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Ear pain04.03.01.003--
Ecchymosis01.01.03.001; 24.07.06.002; 23.06.01.001--Not Available
Eczema23.03.04.006--
Encephalopathy17.13.02.001--
Epistaxis24.07.01.005; 22.04.03.001--
Eye irritation06.04.05.003--Not Available
Fatigue08.01.01.002--
Flatulence07.01.04.002--
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.002--
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gingival bleeding07.09.07.001; 24.07.02.010--Not Available
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