Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydroxyprogesterone
Drug ID BADD_D01106
Description Not Available
Indications and Usage Hydroxyprogesterone caproate is indicated for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. (1)
Marketing Status Not Available
ATC Code G03DA03
DrugBank ID DB14570
KEGG ID D08052
MeSH ID D000077713
PubChem ID 6238
TTD Drug ID D00AEQ
NDC Product Code 73309-243
Synonyms 17 alpha-Hydroxyprogesterone Caproate | 17 alpha Hydroxyprogesterone Caproate | 17-alpha-Hydroxy-Progesterone Caproate | 17 alpha Hydroxy Progesterone Caproate | Caproate, 17-alpha-Hydroxy-Progesterone | Oxyprogesterone Caproate | Hydroxyprogesterone Caproate | Hydroxyprogesterone Hexanoate | 17 alpha-Oxyprogesterone Capronate | 17 alpha Oxyprogesterone Capronate | 17-Hydroxyprogesterone Capronate | 17 Hydroxyprogesterone Capronate | Prolutin Depot | Proluton Depot | Neolutin | Makena | Delalutin
Chemical Information
Molecular Formula C21H30O3
CAS Registry Number 68-96-2
SMILES CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Premature rupture of membranes18.07.01.003--Not Available
Pruritus23.03.12.001--
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Rash23.03.13.001--Not Available
Stillbirth18.01.02.002; 08.04.01.006--Not Available
Swelling08.01.03.015--Not Available
Urinary tract infection11.01.14.004; 20.08.02.001--
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Injection site cellulitis23.09.01.009; 12.07.03.037; 11.02.01.012; 08.02.03.037--Not Available
Injection site swelling12.07.03.018; 08.02.03.017--Not Available
Injection site nodule23.07.04.009; 12.07.03.034; 08.02.03.034--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
Breast disorder21.05.04.004--Not Available
Complication of pregnancy18.02.02.003--Not Available
Shortened cervix21.06.01.009--Not Available
Gestational hypertension24.08.07.004; 18.02.03.004--Not Available
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