Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Griseofulvin
Drug ID BADD_D01042
Description An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Indications and Usage For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
Marketing Status Discontinued; Prescription
ATC Code D01AA08; D01BA01
DrugBank ID DB00400
KEGG ID D00209
MeSH ID D006118
PubChem ID 441140
TTD Drug ID D0C1SF
NDC Product Code 0781-5514; 60264-310; 0472-0013; 64980-186; 62135-496; 62135-495; 64980-185; 64980-184; 0781-5515; 49452-3363; 42794-012; 62135-494
Synonyms Griseofulvin | Grisefuline | Gris-PEG | Gris PEG | GrisPEG | Grisactin | Fulvicin-U-F | Fulvicin U F | FulvicinUF | Grifulvin V
Chemical Information
Molecular Formula C17H17ClO6
CAS Registry Number 126-07-8
SMILES CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Asthenia08.01.01.001--Not Available
Coagulopathy01.01.02.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Erythema23.03.06.001--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Headache17.14.01.0010.003837%
Hepatitis09.01.07.004--Not Available
Hyperbilirubinaemia01.06.04.003; 14.11.01.010; 09.01.01.003--Not Available
Hypersensitivity10.01.03.003--
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Lymphadenopathy01.09.01.0020.003837%Not Available
Nausea07.01.07.001--
Nephrotic syndrome20.05.01.002--
Neuropathy peripheral17.09.03.003--Not Available
Oral candidiasis07.05.07.001; 11.03.03.004--Not Available
Paraesthesia17.02.06.005--
Pemphigoid23.03.01.004; 10.04.02.0020.002558%Not Available
Proteinuria20.02.01.0110.002558%
Pyrexia08.05.02.0030.002558%
Rash23.03.13.0010.002558%Not Available
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