| Pharmaceutical Information |
| Drug Name |
Goserelin acetate |
| Drug ID |
BADD_D01039 |
| Description |
Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state. When the medication is stopped, hormone levels return to normal. |
| Indications and Usage |
Used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. |
| Marketing Status |
Prescription |
| ATC Code |
L02AE03 |
| DrugBank ID |
DB00014
|
| KEGG ID |
D00573
|
| MeSH ID |
D017273
|
| PubChem ID |
16052011
|
| TTD Drug ID |
D00BCG
|
| NDC Product Code |
60440-0960; 50090-3466 |
| Synonyms |
Goserelin | ICI-118630 | ICI 118630 | ICI118630 | Zoladex | Goserelin Acetate | Acetate, Goserelin |
|
| Chemical Information |
| Molecular Formula |
C61H88N18O16 |
| CAS Registry Number |
145781-92-6 |
| SMILES |
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NNC(=O)N)NC(=O)C(COC(C)(C)C)NC(=O)C(
CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C
6CCC(=O)N6.CC(=O)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
