Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ganciclovir sodium
Drug ID BADD_D01004
Description An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Indications and Usage For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Marketing Status Prescription; Discontinued
ATC Code J05AB06; S01AD09
DrugBank ID DB01004
KEGG ID D04301
MeSH ID D015774
PubChem ID 23700083
TTD Drug ID D05ARP
NDC Product Code 51817-171; 25021-185; 63323-315; 0004-6941; 61269-450; 0143-9299; 70436-089; 46014-1054
Synonyms Ganciclovir | Gancyclovir | BW-759 | Ganciclovir Sodium | Ganciclovir, Monosodium Salt | RS-21592 | BIOLF-62 | Cytovene
Chemical Information
Molecular Formula C9H12N5NaO4
CAS Registry Number 84245-13-6
SMILES C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Testicular failure21.13.01.004; 05.05.02.001--Not Available
Thinking abnormal17.02.05.023; 19.10.03.001--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Torsade de pointes02.03.04.005--Not Available
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria23.04.02.001; 10.01.06.001--
Vasculitis24.05.02.001; 10.02.02.006--
Ventricular tachycardia02.03.04.010--
Visual impairment06.02.06.008--Not Available
Vitreous disorder06.08.03.006--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Inappropriate antidiuretic hormone secretion14.05.07.001; 05.03.03.001--Not Available
Vasodilation procedure25.03.01.001--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Foetal disorder18.03.02.001--Not Available
Haematotoxicity12.03.01.025; 01.05.01.007--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Psychotic disorder19.03.01.002--
Renal impairment20.01.03.010--Not Available
Gene mutation03.12.02.002--Not Available
Device related infection11.01.08.018; 08.07.01.005--
Bone marrow failure01.03.03.005--
Device related sepsis11.01.11.008; 08.07.01.004--Not Available
Candida infection11.03.03.021--
Multiple organ dysfunction syndrome08.01.03.057--
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