Pharmaceutical Information |
Drug Name |
Gabapentin enacarbil |
Drug ID |
BADD_D00982 |
Description |
Gabapentin enacarbil is marketed under the name Horizant. It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). |
Indications and Usage |
For the treatment of adult Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). |
Marketing Status |
Prescription |
ATC Code |
N03AX12 |
DrugBank ID |
DB08872
|
KEGG ID |
D09539
|
MeSH ID |
C493250
|
PubChem ID |
9883933
|
TTD Drug ID |
D05KBU
|
NDC Product Code |
53451-0103; 70966-0011; 49187-0710; 53451-0101; 66039-945 |
Synonyms |
1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid | gabapentin enacarbil | XP 12464 | XP12464 | XP-12464 | XP 10569 | XP10569 | XP-10569 | XP 11239 | XP11239 | XP-11239 | XP 13512 | XP13512 | XP-13512 | XP 11084 | XP11084 | XP-11084 |
|
Chemical Information |
Molecular Formula |
C16H27NO6 |
CAS Registry Number |
478296-72-9 |
SMILES |
CC(C)C(=O)OC(C)OC(=O)NCC1(CCCCC1)CC(=O)O |
Chemical Structure |
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ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
|
ADRs Induced by Drug |
ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
Acute kidney injury | 20.01.03.016 | 0.006362% | | | Infantile back arching | 18.04.01.017; 15.03.01.025 | 0.044532% | | Not Available |
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