Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fragmin
Drug ID BADD_D00974
Description Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000. LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than unfractionated heparin. Dalteparin can also be safely used in most pregnant women. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
Indications and Usage It is also used in the prevention of clotting during hemodialysis and hemofiltration in connection with acute renal failure or chronic renal insufficiency.
Marketing Status Prescription; Discontinued
ATC Code B01AB04
DrugBank ID DB06779
KEGG ID D03353
MeSH ID D017985
PubChem ID Not Available
TTD Drug ID D08PSU
NDC Product Code Not Available
Synonyms Dalteparin | Tedelparin | FR-860 | FR 860 | FR860 | Kabi-2165 | Kabi 2165 | Kabi2165 | Dalteparin Sodium | Sodium, Dalteparin | Fragmin | Fragmine
Chemical Information
Molecular Formula Not Available
CAS Registry Number 9005-49-6
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state19.13.01.001; 17.02.03.005--
Congenital anomaly03.02.01.001--Not Available
Constipation07.02.02.001--
Coronary artery thrombosis24.01.05.002; 02.02.01.007--Not Available
Cyanosis02.01.02.002; 24.03.01.007; 22.02.02.007--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Developmental delay08.01.03.037--Not Available
Diarrhoea07.02.01.001--
Diplegia17.01.04.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Endocrine disorder05.09.01.001--Not Available
Eosinophilia01.02.04.001--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Eye haemorrhage24.07.05.002; 06.07.02.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Foetal distress syndrome18.03.02.003--Not Available
Gangrene24.04.05.003; 23.06.06.001; 11.02.01.003--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.009--Not Available
Gastrointestinal pain07.01.05.005--
Gravitational oedema08.01.07.005; 02.05.04.014--Not Available
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