Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluocinolone acetonide
Drug ID BADD_D00924
Description Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity.[T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also for the treatment of chronic non-infectious uveitis affecting the posterior segment of the eye (Retisert).
Marketing Status Prescription; Discontinued
ATC Code C05AA10; D07AC04; S01BA15; S02BA08
DrugBank ID DB00591
KEGG ID D01825
MeSH ID D005446
PubChem ID 6215
TTD Drug ID D02QJH
NDC Product Code 64980-331; 63629-8655; 51927-0150; 68462-185; 0299-5500; 46439-8709; 64980-330; 51672-1365; 10135-670; 43538-911; 70752-159; 68791-101; 24208-416; 65162-704; 53183-0261; 49452-3156; 68462-591; 65162-703; 43538-900; 0168-0064; 71879-136; 65162-702; 43538-920; 71161-134; 0713-0709; 45802-887; 68791-102; 45802-485; 0395-8243; 43386-069; 43538-910; 71428-002; 70752-158; 0713-0223; 76420-163; 45802-009; 43538-921; 39328-079; 70752-156; 43538-901; 51672-1357; 68611-190; 0713-0224; 68791-103; 63629-8656; 51672-1356; 38779-0022; 68462-590
Synonyms Fluocinolone Acetonide | Acetonide, Fluocinolone | Fluortriamcinolone Acetonide | Acetonide, Fluortriamcinolone | Flurosyn | Jellin | Jellisoft | Synalar | Synalar-HP | Synalar HP | Synemol | Synamol | Alvadermo | Capex | Co-Fluocin | Co Fluocin | Cortiespec | Derma-Smooth FS | Derma Smooth FS | Flucinar | Fluocid | Fluodermo | Fluonid | Fluotrex | Flusolgen | Gelidina
Chemical Information
Molecular Formula C24H30F2O6
CAS Registry Number 67-73-2
SMILES CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Impaired healing08.03.02.001--Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Intraocular pressure decreased13.07.04.0060.002297%Not Available
Intraocular pressure increased13.07.04.0020.042886%Not Available
Iris adhesions06.06.06.003--Not Available
Lacrimation increased06.08.02.004--
Leukoderma23.05.02.001--Not Available
Macular oedema06.04.06.0050.002297%Not Available
Maculopathy06.09.03.007--Not Available
Mania19.16.02.002--
Miliaria23.02.03.014--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervous system disorder17.02.10.001--Not Available
Ocular hypertension06.03.01.0030.001532%Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Otitis media acute04.05.01.002; 11.01.05.005--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Panophthalmitis06.04.05.005--Not Available
Papule23.03.03.038--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Photopsia06.02.06.004; 17.17.01.006--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash papular23.03.13.017--Not Available
Rash pustular23.03.10.003; 11.01.12.002--
The 3th Page    First    Pre   3 4 5    Next   Last    Total 5 Pages