Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferric carboxymaltose
Drug ID BADD_D00882
Description Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. FDA approved on July 25, 2013.
Indications and Usage Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB08917
KEGG ID D08920
MeSH ID C522335
PubChem ID 86278165
TTD Drug ID D02ICI
NDC Product Code 59353-363; 64552-4070; 0517-0620; 42973-330; 14593-923
Synonyms ferric carboxymaltose | iron carboxymaltose | iron dextri-maltose | polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate | Ferinject | VIT-45 | VIT 45 | injectafer
Chemical Information
Molecular Formula C24H44FeO25-
CAS Registry Number 9007-72-1
SMILES C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C(=O)[O-])O)O)CO)CO )O)O)O)O.O.[OH-].[O-2].[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002-
Abdominal pain upper07.01.05.003-
Alanine aminotransferase increased13.03.01.003--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001-
Anaphylactic shock24.06.02.004; 10.01.07.002-Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003-Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anhedonia19.15.02.007-Not Available
Anxiety19.06.02.002-
Arthralgia15.01.02.001-
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005-
Blood iron decreased13.11.01.006-Not Available
Blood pressure decreased13.14.03.002-Not Available
Blood pressure increased13.14.03.005-Not Available
Bone pain15.02.01.001-
Burning sensation17.02.06.001; 08.01.09.029-Not Available
Chest discomfort02.02.02.009; 22.02.08.001; 08.01.08.019-Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011-Not Available
Chills15.05.03.016; 08.01.09.001-
Cold sweat23.02.03.002; 08.01.03.024-Not Available
Constipation07.02.02.001--
Cough22.02.03.001-
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.002-
Death08.04.01.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003-Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007-
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