Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenoprofen
Drug ID BADD_D00877
Description An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Indications and Usage For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
Marketing Status Prescription; Discontinued
ATC Code M01AE04
DrugBank ID DB00573
KEGG ID D02350
MeSH ID D005279
PubChem ID 3342
TTD Drug ID D03XYW
NDC Product Code Not Available
Synonyms Fenoprofen | Fenoprofen Dihydrate, Calcium Salt | Nalgesic | Fenoprofen Calcium | Fenoprofen, Anhydrous, Calcium Salt | Nalfon
Chemical Information
Molecular Formula C15H14O3
CAS Registry Number 29679-58-1
SMILES CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Electrocardiogram abnormal13.14.05.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Glossodynia07.14.02.001--Not Available
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Haematuria20.02.01.006; 24.07.01.047--
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatitis cholestatic09.01.01.002--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Insomnia19.02.01.002; 17.15.03.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Nephrotic syndrome20.05.01.002--
Nervousness19.06.02.003--Not Available
Oedema peripheral08.01.07.007; 02.05.04.007; 14.05.06.011--
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