Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenofibrate
Drug ID BADD_D00873
Description Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Indications and Usage For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Marketing Status Prescription; Discontinued
ATC Code C10AB05
DrugBank ID DB01039
KEGG ID D00565
MeSH ID D011345
PubChem ID 3339
TTD Drug ID D07XGR
NDC Product Code 68180-746; 0378-3065; 0115-0522; 46708-555; 27241-117; 71335-0891; 0115-1523; 68071-2587; 13672-020; 13668-439; 62332-361; 70934-567; 27241-116; 62332-555; 42291-292; 66869-137; 51407-094; 68543-3189; 0074-3189; 0378-3066; 16714-741; 46708-086; 31722-596; 70934-508; 68180-745; 65862-769; 71610-027; 16714-163; 50090-3044; 0378-7100; 0904-6810; 60505-3120; 51407-204; 42385-950; 66064-1006; 71335-1286; 71205-366; 50090-5401; 68180-130; 55111-395; 27241-120; 68071-2540; 71205-949; 62559-461; 69238-1261; 31722-595; 62559-305; 0378-7101; 50090-5796; 0115-0511; 43975-305; 50268-313; 42858-067; 68071-4692; 0904-7128; 68071-4992; 70518-3370; 62332-554; 68382-269; 43547-430; 35561-347; 63304-901; 27437-109; 16714-162; 17337-0410; 69238-1262; 62332-351; 68294-0001; 70518-2907; 43975-444; 50090-1275; 63304-449; 62332-539; 55111-349; 68180-231; 70518-2947; 51407-205; 59651-203; 59651-201; 62332-085; 62332-350; 63187-681; 69844-008; 42385-935; 68071-4983; 63304-444; 65862-768; 69097-458; 70966-0021; 68788-7579; 68180-360; 68382-270; 13668-438; 72189-172; 68071-3114; 68071-4310; 68462-581; 50090-4121; 71205-050; 50090-5854; 46708-351; 59349-0018; 62559-306; 50090-1274; 71335-0741; 69097-894; 60687-629; 42858-200; 69097-895; 35561-345; 68084-835; 46708-085; 60687-618; 68071-4358; 0074-3173; 51079-608; 50090-5327; 68788-7932; 63629-7213; 13668-440; 51407-091; 51407-092; 35561-346; 60760-411; 62332-360; 50090-3887; 50090-3842; 69238-1263; 51079-599; 68071-1601; 68084-827; 63629-2505; 42291-290; 70934-638; 70518-0700; 42858-660; 27241-118; 11014-0132; 71205-190; 68071-4264; 42385-951; 50268-309; 71335-1292; 71335-1756; 59651-202; 63629-1514; 68012-490; 0115-1522; 50090-4957; 49452-3101; 70756-214; 69844-013; 0378-4390; 16714-739; 68071-4320; 42385-936; 68084-329; 46708-857; 68071-5101; 63629-1099; 0904-7161; 68180-232; 63187-760; 46708-554; 50090-4698; 50090-3373; 46708-350; 27437-108; 46708-084; 0615-8270; 62332-086; 68788-8106; 17337-0019; 70934-223; 50090-2899; 68071-4182; 66869-147; 16714-740; 68180-131; 63187-640; 60760-318; 45802-315; 50268-312; 43353-898; 68084-328; 43598-910; 68543-3173; 70756-215; 51407-090; 72189-026; 62332-538; 17337-0430; 69367-257; 68012-495; 46708-361; 68462-582; 68682-495; 62332-084; 60760-660; 63304-443; 42291-289; 43598-909; 70518-2768; 43547-431; 27437-107; 0115-0533; 62559-460; 70934-224; 55700-876; 68071-4991; 11722-065; 50090-5244; 65977-0074; 70934-591; 63629-1100; 45802-132; 0378-4391; 69844-012; 69367-254; 42858-454; 68788-7662; 69367-269; 63629-1101; 27241-119; 71335-0872; 68180-389; 68071-4289; 60505-3121; 71335-2016; 50090-4031; 69367-270; 68180-363; 43353-272; 63187-940; 68071-2369; 69844-009; 69097-459; 50090-3904; 68180-362; 27437-110; 68084-635; 63304-448; 69097-896; 42858-134; 50090-2546; 58175-0348; 71335-1701; 69238-1260; 46708-360; 0115-5511; 63304-900; 0115-5522; 11014-0131; 68788-7578; 43353-001; 43975-306; 50090-5158; 51407-093; 68180-361; 69367-268; 53747-033; 68682-490; 68462-580; 70518-2349; 68071-4988; 68788-7816; 70518-1988; 68180-388
Synonyms Fenofibrate | Phenofibrate | Procetofene | Procetofen | Apo-Feno-Micro | Apo Feno Micro | Apo-Fenofibrate | Apo Fenofibrate | CiL | Controlip | durafenat | Fenobeta | Fenofanton | Fenofibrat AbZ | Fenofibrat AL | Fenofibrat AZU | AZU, Fenofibrat | Fenofibrat Heumann | Heumann, Fenofibrat | Fenofibrat Hexal | Hexal, Fenofibrat | Fenofibrat Stada | Stada, Fenofibrat | fenofibrat von ct | Fenofibrat-ratiopharm | Fenofibrat ratiopharm | Fénofibrate MSD | Gen-Fenofibrate | Gen Fenofibrate | LF-178 | LF 178 | LF178 | Lipanthyl | Lipantil | Fenofibrat FPh | Lipidil | Secalip | Supralip | Fénofibrate Debat | Debat, Fénofibrate | Lipidil-Ter | Lipidil Ter | Liparison | Livesan | Lofibra | MTW-Fenofibrat | MTW Fenofibrat | Novo-Fenofibrate | Novo Fenofibrate | Nu-Fenofibrate | Nu Fenofibrate | PMS-Fenofibrate Micro | PMS Fenofibrate Micro | Tricor | Normalip | Antara Micronized Procetofen | Micronized Procetofen, Antara | Procetofen, Antara Micronized
Chemical Information
Molecular Formula C20H21ClO4
CAS Registry Number 49562-28-9
SMILES CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.000259%
Oesophagitis07.08.05.001--
Osteoarthritis15.01.04.001--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pallor23.03.03.031; 08.01.03.032; 24.03.04.0010.000173%Not Available
Palpitations02.01.02.003--
Pancreatic carcinoma16.13.10.001; 07.21.09.0020.000345%Not Available
Pancreatitis07.18.01.0010.000173%
Pancreatitis acute07.18.01.0020.001467%Not Available
Papule23.03.03.0380.000173%Not Available
Paraesthesia17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Peripheral vascular disorder24.03.01.003--Not Available
Pharyngeal oedema23.04.01.016; 10.01.05.016; 22.04.05.0030.000173%Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Phlebitis24.05.03.001; 12.02.01.002--
Photosensitivity reaction23.03.09.0030.002502%
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Prostatic disorder21.04.01.001--Not Available
Protein total increased13.09.01.0050.000173%Not Available
Pruritus23.03.12.0010.001208%
Pulmonary embolism24.01.06.001; 22.06.02.0010.000518%Not Available
Pulmonary infarction24.04.09.001; 22.06.02.0020.000173%Not Available
Pyrexia08.05.02.0030.001208%
Rash23.03.13.0010.000949%Not Available
Rash erythematous23.03.06.0030.000690%Not Available
Rash generalised23.03.13.0020.000173%Not Available
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