Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenofibrate
Drug ID BADD_D00873
Description Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Indications and Usage For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Marketing Status Prescription; Discontinued
ATC Code C10AB05
DrugBank ID DB01039
KEGG ID D00565
MeSH ID D011345
PubChem ID 3339
TTD Drug ID D07XGR
NDC Product Code 68180-746; 0378-3065; 0115-0522; 46708-555; 27241-117; 71335-0891; 0115-1523; 68071-2587; 13672-020; 13668-439; 62332-361; 70934-567; 27241-116; 62332-555; 42291-292; 66869-137; 51407-094; 68543-3189; 0074-3189; 0378-3066; 16714-741; 46708-086; 31722-596; 70934-508; 68180-745; 65862-769; 71610-027; 16714-163; 50090-3044; 0378-7100; 0904-6810; 60505-3120; 51407-204; 42385-950; 66064-1006; 71335-1286; 71205-366; 50090-5401; 68180-130; 55111-395; 27241-120; 68071-2540; 71205-949; 62559-461; 69238-1261; 31722-595; 62559-305; 0378-7101; 50090-5796; 0115-0511; 43975-305; 50268-313; 42858-067; 68071-4692; 0904-7128; 68071-4992; 70518-3370; 62332-554; 68382-269; 43547-430; 35561-347; 63304-901; 27437-109; 16714-162; 17337-0410; 69238-1262; 62332-351; 68294-0001; 70518-2907; 43975-444; 50090-1275; 63304-449; 62332-539; 55111-349; 68180-231; 70518-2947; 51407-205; 59651-203; 59651-201; 62332-085; 62332-350; 63187-681; 69844-008; 42385-935; 68071-4983; 63304-444; 65862-768; 69097-458; 70966-0021; 68788-7579; 68180-360; 68382-270; 13668-438; 72189-172; 68071-3114; 68071-4310; 68462-581; 50090-4121; 71205-050; 50090-5854; 46708-351; 59349-0018; 62559-306; 50090-1274; 71335-0741; 69097-894; 60687-629; 42858-200; 69097-895; 35561-345; 68084-835; 46708-085; 60687-618; 68071-4358; 0074-3173; 51079-608; 50090-5327; 68788-7932; 63629-7213; 13668-440; 51407-091; 51407-092; 35561-346; 60760-411; 62332-360; 50090-3887; 50090-3842; 69238-1263; 51079-599; 68071-1601; 68084-827; 63629-2505; 42291-290; 70934-638; 70518-0700; 42858-660; 27241-118; 11014-0132; 71205-190; 68071-4264; 42385-951; 50268-309; 71335-1292; 71335-1756; 59651-202; 63629-1514; 68012-490; 0115-1522; 50090-4957; 49452-3101; 70756-214; 69844-013; 0378-4390; 16714-739; 68071-4320; 42385-936; 68084-329; 46708-857; 68071-5101; 63629-1099; 0904-7161; 68180-232; 63187-760; 46708-554; 50090-4698; 50090-3373; 46708-350; 27437-108; 46708-084; 0615-8270; 62332-086; 68788-8106; 17337-0019; 70934-223; 50090-2899; 68071-4182; 66869-147; 16714-740; 68180-131; 63187-640; 60760-318; 45802-315; 50268-312; 43353-898; 68084-328; 43598-910; 68543-3173; 70756-215; 51407-090; 72189-026; 62332-538; 17337-0430; 69367-257; 68012-495; 46708-361; 68462-582; 68682-495; 62332-084; 60760-660; 63304-443; 42291-289; 43598-909; 70518-2768; 43547-431; 27437-107; 0115-0533; 62559-460; 70934-224; 55700-876; 68071-4991; 11722-065; 50090-5244; 65977-0074; 70934-591; 63629-1100; 45802-132; 0378-4391; 69844-012; 69367-254; 42858-454; 68788-7662; 69367-269; 63629-1101; 27241-119; 71335-0872; 68180-389; 68071-4289; 60505-3121; 71335-2016; 50090-4031; 69367-270; 68180-363; 43353-272; 63187-940; 68071-2369; 69844-009; 69097-459; 50090-3904; 68180-362; 27437-110; 68084-635; 63304-448; 69097-896; 42858-134; 50090-2546; 58175-0348; 71335-1701; 69238-1260; 46708-360; 0115-5511; 63304-900; 0115-5522; 11014-0131; 68788-7578; 43353-001; 43975-306; 50090-5158; 51407-093; 68180-361; 69367-268; 53747-033; 68682-490; 68462-580; 70518-2349; 68071-4988; 68788-7816; 70518-1988; 68180-388
Synonyms Fenofibrate | Phenofibrate | Procetofene | Procetofen | Apo-Feno-Micro | Apo Feno Micro | Apo-Fenofibrate | Apo Fenofibrate | CiL | Controlip | durafenat | Fenobeta | Fenofanton | Fenofibrat AbZ | Fenofibrat AL | Fenofibrat AZU | AZU, Fenofibrat | Fenofibrat Heumann | Heumann, Fenofibrat | Fenofibrat Hexal | Hexal, Fenofibrat | Fenofibrat Stada | Stada, Fenofibrat | fenofibrat von ct | Fenofibrat-ratiopharm | Fenofibrat ratiopharm | Fénofibrate MSD | Gen-Fenofibrate | Gen Fenofibrate | LF-178 | LF 178 | LF178 | Lipanthyl | Lipantil | Fenofibrat FPh | Lipidil | Secalip | Supralip | Fénofibrate Debat | Debat, Fénofibrate | Lipidil-Ter | Lipidil Ter | Liparison | Livesan | Lofibra | MTW-Fenofibrat | MTW Fenofibrat | Novo-Fenofibrate | Novo Fenofibrate | Nu-Fenofibrate | Nu Fenofibrate | PMS-Fenofibrate Micro | PMS Fenofibrate Micro | Tricor | Normalip | Antara Micronized Procetofen | Micronized Procetofen, Antara | Procetofen, Antara Micronized
Chemical Information
Molecular Formula C20H21ClO4
CAS Registry Number 49562-28-9
SMILES CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood bilirubin increased13.03.01.0080.000259%
Blood cholesterol increased13.12.01.0020.000173%
Blood creatine phosphokinase increased13.04.01.0010.001294%
Blood creatinine increased13.13.01.0040.000345%
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006--Not Available
Blood uric acid increased13.02.04.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bradycardia02.03.02.0020.000173%Not Available
Breast feeding26.05.01.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Burning sensation17.02.06.001; 08.01.09.0290.000259%Not Available
Bursitis15.04.01.001--Not Available
Calculus urinary20.04.02.001--Not Available
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Cataract06.06.01.001--
Cellulitis23.09.01.001; 11.02.01.0010.000173%Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.0010.000259%
Cholecystitis09.03.01.001--
Cholelithiasis09.03.01.0020.000259%Not Available
Cholestasis09.01.01.0010.000518%Not Available
Chromaturia20.02.01.0020.000345%
Cirrhosis alcoholic09.01.04.005--Not Available
Colitis07.08.01.0010.000259%
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coronary artery disease24.04.04.006; 02.02.01.001--Not Available
Cough22.02.03.001--
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