Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Famciclovir
Drug ID BADD_D00868
Description Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Indications and Usage For the treatment of acute herpes zoster (shingles). Also for the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
Marketing Status Prescription; Discontinued
ATC Code J05AB09; S01AD07
DrugBank ID DB00426
KEGG ID D00317
MeSH ID D000077595
PubChem ID 3324
TTD Drug ID D0VT8P
NDC Product Code 64980-350; 33342-024; 42291-416; 60505-3247; 63187-919; 31722-706; 16714-615; 65862-466; 16714-616; 65977-0047; 60429-361; 63187-998; 60429-359; 17856-0705; 63629-7890; 65862-465; 31722-707; 65862-486; 64980-349; 72969-027; 60505-3246; 0093-8118; 71205-609; 16714-614; 0093-8119; 17856-0706; 53104-7616; 65862-467; 55289-168; 60429-360; 33342-026; 33342-025; 63187-920; 71052-199; 60505-3245; 42291-415; 31722-708; 17856-0708; 69875-8015; 0093-8117; 42291-414; 64980-351
Synonyms Famciclovir | 9-(4-Acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine | 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester) | BRL 42810 | BRL-42810 | BRL42810 | Famvir
Chemical Information
Molecular Formula C14H19N5O4
CAS Registry Number 104227-87-4
SMILES CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Fungal infection11.03.05.001--Not Available
Gamma-glutamyltransferase increased13.03.01.011--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Herpes zoster23.09.03.002; 11.05.02.003--
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity vasculitis24.05.02.012; 10.02.02.017; 23.06.02.005; 01.01.04.008--Not Available
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Jaundice09.01.01.004; 01.06.04.004; 23.03.03.030--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Laryngeal pain22.02.05.036--
Leukopenia01.02.02.001--Not Available
Lipase increased13.05.01.003--
Liver function test abnormal13.03.01.013--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Myalgia15.05.02.001--
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.004--Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
The 2th Page    First    Pre   2 3    Next   Last    Total 3 Pages