Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cellulitis staphylococcal23.09.01.013; 11.02.05.0060.001650%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.02.08.003; 02.02.02.011; 08.01.08.0020.037945%Not Available
Chills15.05.03.016; 08.01.09.001--
Chloasma23.05.01.001; 18.08.02.002--Not Available
Cholelithiasis09.03.01.002--Not Available
Cholestasis09.01.01.001--Not Available
Chromaturia20.02.01.002--
Cold sweat23.02.03.002; 08.01.03.024--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cough22.02.03.001--
Crying19.04.02.002; 17.02.05.013; 08.01.03.005; 12.02.11.0010.010311%Not Available
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.002--
Cyst16.02.02.002; 08.03.05.0010.002062%Not Available
Cystitis20.03.02.002; 11.01.14.001--
Deafness04.02.01.001--Not Available
Death08.04.01.001--
Death neonatal18.04.01.002; 08.04.01.0020.000215%
Dehydration14.05.05.001--
Depressed mood19.15.02.0010.016498%Not Available
Depression19.15.01.0010.068879%
Depression suicidal19.15.01.0040.000825%Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.003300%Not Available
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005--Not Available
Discomfort08.01.08.0030.066405%Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
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