Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etodolac
Drug ID BADD_D00850
Description Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Indications and Usage For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
Marketing Status Prescription; Discontinued
ATC Code M01AB08
DrugBank ID DB00749
KEGG ID D00315
MeSH ID D017308
PubChem ID 3308
TTD Drug ID D0N1WU
NDC Product Code 51655-423; 60760-378; 17373-1086; 61919-251; 71335-0126; 43353-918; 51672-4051; 63629-1935; 63187-374; 43063-834; 0185-0687; 55700-592; 63629-8805; 57451-1161; 60429-312; 71335-0982; 50090-3974; 60505-0040; 43353-749; 43063-578; 43063-856; 70518-3116; 55700-757; 60429-244; 60429-315; 43353-753; 71335-0399; 61919-092; 71205-467; 51672-4052; 66267-575; 63187-796; 60760-552; 71335-0602; 68788-7315; 76385-118; 68382-272; 61919-784; 68382-271; 70518-3163; 60429-314; 43353-752; 62559-251; 50090-3963; 68382-273; 60505-0039; 0093-1118; 63187-736; 60429-313; 69238-1342; 63629-8598; 65841-779; 42291-405; 43063-671; 62559-250; 63187-793; 50090-0613; 50090-1789; 42291-404; 42799-111; 80425-0140; 35356-711; 63629-3641; 51672-4018; 70934-282; 63629-1936; 43353-294; 60429-311; 69238-1343; 51672-4053; 60429-243; 50090-4053; 65841-778; 71335-1958; 68788-7300; 80425-0181; 60505-0041; 51672-4036; 80425-0126; 12658-0580; 16714-499; 65841-777; 0093-1122; 60760-298; 51672-4016; 50090-2133; 71205-140; 16714-498; 16714-497; 51672-4017; 50090-1790; 71335-1230; 67296-1271; 69306-020; 17373-1087; 58793-010; 42799-112; 61919-858; 0185-0675; 67628-1001; 0093-7172; 60505-0102; 76385-119
Synonyms Etodolac | Etodolic Acid | Etodolac, (+-)-Isomer | Etodolac, (-)-Isomer | Etodolac, (S)-Isomer | Ultradol | Etodolac, Monosodium Salt, (+-) Isomer | Etodolac, Monosodium Salt, (S)-Isomer | Lodine | Ramodar | AY-24,236 | AY 24,236 | AY-24236 | AY 24236 | Etodolac, Monosodium Salt
Chemical Information
Molecular Formula C17H21NO3
CAS Registry Number 41340-25-4
SMILES CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis23.06.02.005; 24.05.02.012; 10.02.02.017; 01.01.04.008--Not Available
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Intestinal ulcer07.04.06.003--Not Available
Irritability19.04.02.013; 08.01.03.011--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.0040.000989%Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Lung infiltration22.01.02.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.0030.000989%
Melaena24.07.02.013; 07.12.02.004--Not Available
Meningitis17.06.03.001; 11.01.03.001--
Metabolic acidosis14.01.01.0030.000989%Not Available
Mouth ulceration07.05.06.004--Not Available
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.0010.001484%
Nephrolithiasis20.04.01.002--
Nervousness19.06.02.003--Not Available
Neutropenia01.02.03.004--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Oesophageal achalasia07.02.03.004--Not Available
Oesophagitis07.08.05.001--
Oliguria20.01.03.004--Not Available
The 4th Page    First    Pre   4 5 6 7    Next   Last    Total 7 Pages