| Drug Name |
Efavirenz |
| Drug ID |
BADD_D00749 |
| Description |
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.
Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission. |
| Indications and Usage |
For use in combination treatment of HIV infection (AIDS) |
| Marketing Status |
approved; investigational |
| ATC Code |
J05AG03 |
| DrugBank ID |
DB00625
|
| KEGG ID |
D00896
|
| MeSH ID |
C098320
|
| PubChem ID |
64139
|
| TTD Drug ID |
D07HVY
|
| NDC Product Code |
48087-0127; 65862-105; 68554-0018; 65862-049; 69097-301; 72865-172; 70966-0025; 31722-504; 48087-0131; 65015-641; 67835-0001; 12783-0510; 65862-324; 65862-106; 65862-267; 69988-0008; 0056-0474; 53104-7544; 65675-1584; 68554-0042; 42543-889; 64380-889; 65862-104; 70518-3258; 64980-406; 48087-0062; 65015-868; 76302-021; 51407-382; 64980-407; 70518-2962; 48087-0128; 64220-195; 65015-859; 70366-002; 0056-0470; 65015-836 |
| UNII |
JE6H2O27P8
|
| Synonyms |
efavirenz | (s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one | efavirenz, (S)-isomer | efavirenz, (R)-isomer | Stocrin | Sustiva | DMP 266 | DMP-266 | L 743726 | L-743726 | L 743,726 | L-743,726 |
