Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Domperidone
Drug ID BADD_D00705
Description A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Indications and Usage For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
Marketing Status approved; investigational; vet_approved
ATC Code A03FA03
DrugBank ID DB01184
KEGG ID D01745; D07868
MeSH ID D004294
PubChem ID 3151
TTD Drug ID D0AV3G
NDC Product Code 66326-101
UNII 5587267Z69
Synonyms Domperidone | Domperidon | Domidon | Domperidon AL | Domperidon Hexal | Hexal, Domperidon | Domperidon Stada | Stada, Domperidon | Domperidon-TEVA | Domperidon TEVA | Domperidona Gamir | Gamir, Domperidona | Domperidone Maleate | Maleate, Domperidone | Domperidone Maleate (1:1) | Domperidone Monohydrochloride | Monohydrochloride, Domperidone | Gastrocure | Motilium | Nauzelin | Novo-Domperidone | Novo Domperidone | Nu-Domperidone | Nu Domperidone | PMS-Domperidone | PMS Domperidone | Péridys | R-33,812 | R33,812 | R-33812 | R33812 | Ratio-Domperidone | Ratio Domperidone | Apo-Domperidone | Apo Domperidone
Chemical Information
Molecular Formula C22H24ClN5O2
CAS Registry Number 57808-66-9
SMILES C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Extrasystoles02.03.02.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gait disturbance08.01.02.002; 15.03.05.013; 17.02.05.016--
Galactorrhoea21.05.02.002; 05.03.04.002--Not Available
Gynaecomastia05.05.02.003; 21.05.04.003--
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Hypotension24.06.03.002--
Injection site pain08.02.03.010; 12.07.03.011--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Joint swelling15.01.02.004--Not Available
Lethargy17.02.04.003; 08.01.01.008; 19.04.04.004--
Menopausal symptoms21.02.02.002--Not Available
Menstruation irregular21.01.01.005; 05.05.01.008--
Migraine24.03.05.003; 17.14.02.001--Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain in extremity15.03.04.010--
Palpitations02.11.04.012--
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