Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dipyridamole
Drug ID BADD_D00692
Description A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indications and Usage For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Marketing Status Prescription; Discontinued
ATC Code B01AC07
DrugBank ID DB00975
KEGG ID D00302
MeSH ID D004176
PubChem ID 3108
TTD Drug ID D0F9GE
NDC Product Code 62559-236; 64980-133; 0115-1070; 62559-237; 69584-182; 65841-664; 64980-135; 65404-005; 65015-782; 65841-662; 51407-628; 0115-1071; 0527-1461; 51662-1447; 69584-183; 65841-663; 62559-235; 0641-2569; 0527-1463; 51407-626; 68166-003; 0404-9852; 66039-917; 0527-1462; 71205-894; 52584-569; 51927-1571; 51407-627; 70896-2025; 68382-187; 0115-1072; 68382-188; 68382-189; 12660-0084; 69584-181; 17511-122; 64980-134; 71205-896; 71205-895
Synonyms Dipyridamole | Dipyramidole | Apo-Dipyridamole | Apo Dipyridamole | Cerebrovase | Persantine | Persantin | Curantil | Curantyl | Kurantil | Miosen | Novo-Dipiradol | Novo Dipiradol | Antistenocardin | Cléridium
Chemical Information
Molecular Formula C24H40N8O4
CAS Registry Number 58-32-2
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cholelithiasis09.03.01.002--Not Available
Circulatory collapse24.06.02.0010.006711%Not Available
Coma17.02.09.0010.004474%Not Available
Coordination abnormal17.02.02.004--Not Available
Coronary artery disease24.04.04.006; 02.02.01.001--Not Available
Cough22.02.03.001--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.0030.004474%
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Dyspnoea22.02.01.004; 02.01.03.002--
Ear pain04.03.01.003--
Electrocardiogram abnormal13.14.05.001--Not Available
Epistaxis22.04.03.001; 24.07.01.0050.004474%
Eructation07.01.02.003--
Extrasystoles02.03.02.003--Not Available
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.0010.001167%Not Available
Gastrointestinal pain07.01.05.005--
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 6 Pages