Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status Prescription; Discontinued
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 38779-0324; 0575-6200; 58159-039; 52952-003; 69575-4025; 62991-2857; 49452-2541; 51927-2742; 38779-3184; 71052-664; 0254-1010; 13517-100; 14501-0096; 45562-1740; 51552-1582
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Headache17.14.01.001--
Herpes virus infection11.05.02.008--Not Available
Hirsutism23.02.04.001; 05.05.01.005--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertrichosis23.02.04.0020.000969%
Hypoglycaemia14.06.03.001; 05.06.03.0010.001615%
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Ileus07.13.01.001--
Insomnia19.02.01.002; 17.15.03.002--
Ketoacidosis14.01.01.008--Not Available
Lacrimation increased06.08.02.004--
Leukopenia01.02.02.001--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Loss of consciousness17.02.04.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Nephrotic syndrome20.05.01.002--
Nocturia20.02.03.001--Not Available
Oedema14.05.06.010; 08.01.07.0060.000168%Not Available
Oedema peripheral02.05.04.007; 14.05.06.011; 08.01.07.0070.000646%
Optic nerve infarction24.04.10.003; 06.07.03.003--Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Pain08.01.08.004--
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