Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Delavirdine mesylate
Drug ID BADD_D00604
Description A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Indications and Usage For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
Marketing Status Prescription
ATC Code J05AG02
DrugBank ID DB00705
KEGG ID D00895
MeSH ID D020008
PubChem ID 441386
TTD Drug ID D0G6SD
NDC Product Code Not Available
Synonyms Delavirdine | Rescriptor | U-90152 | U 90152 | U90152 | U-90152S | U 90152S | U90152S | Delavirdine Mesylate | Mesylate, Delavirdine
Chemical Information
Molecular Formula C23H32N6O6S2
CAS Registry Number 147221-93-0
SMILES CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C.CS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Fatigue08.01.01.002--
Flatulence07.01.04.002--
Folliculitis23.09.04.007; 11.01.12.018--
Fungal skin infection11.03.05.002; 23.09.02.001--Not Available
Gamma-glutamyltransferase increased13.03.01.011--
Gastrooesophageal reflux disease07.02.02.003--
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal candidiasis11.03.03.011; 07.19.02.003--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Generalised oedema14.05.06.007; 08.01.07.004--
Gingival bleeding24.07.02.010; 07.09.07.001--Not Available
Gingivitis11.01.04.013; 07.09.03.003--
Glossitis07.14.01.001--Not Available
Granulocytosis01.02.01.008--Not Available
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Haematospermia24.07.03.008; 21.03.03.003--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Heart rate abnormal13.14.04.006--Not Available
Hepatic failure09.01.03.002--
Hepatitis09.01.07.004--Not Available
Hepatomegaly09.01.05.001--Not Available
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Herpes zoster23.09.03.002; 11.05.02.003--
Hiccups22.02.04.002; 07.01.06.009--
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