Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Daunorubicin citrate
Drug ID BADD_D00591
Description A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Indications and Usage For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.
Marketing Status Prescription; Discontinued
ATC Code L01DB02
DrugBank ID DB00694
KEGG ID D10787
MeSH ID D003630
PubChem ID 9961878
TTD Drug ID D01XWG
NDC Product Code Not Available
Synonyms Daunorubicin | Daunomycin | Rubomycin | Dauno-Rubidomycine | Dauno Rubidomycine | Rubidomycin | Daunoblastin | Daunoblastine | NSC-82151 | NSC 82151 | NSC82151 | Cerubidine | Daunorubicin Hydrochloride | Hydrochloride, Daunorubicin
Chemical Information
Molecular Formula C33H37NO17
CAS Registry Number 371770-68-2
SMILES CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O. C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gait disturbance17.02.05.016; 08.01.02.002--
Gastritis07.08.02.001--
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gingival bleeding24.07.02.010; 07.09.07.001--Not Available
Haemoptysis02.01.02.006; 24.07.01.006; 22.02.03.004--Not Available
Haemorrhoids24.10.02.002; 07.15.03.001--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatomegaly09.01.05.001--Not Available
Hiccups07.01.06.009; 22.02.04.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Increased appetite08.01.09.027; 14.03.01.003--Not Available
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Lung infiltration22.01.02.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Melaena24.07.02.013; 07.12.02.004--Not Available
Meningitis17.06.03.001; 11.01.03.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Neuropathy peripheral17.09.03.003--Not Available
Nocturia20.02.03.001--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Palpitations02.01.02.003--
Pericardial effusion02.06.01.002--
Polyuria20.02.03.002--Not Available
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