Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dalfampridine
Drug ID BADD_D00574
Description Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Indications and Usage Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS).
Marketing Status Prescription
ATC Code N07XX07
DrugBank ID DB06637
KEGG ID D04127
MeSH ID D015761
PubChem ID 1727
TTD Drug ID D08YIN
NDC Product Code 38779-3205; 42571-338; 63190-0510; 46016-5042; 16729-292; 56125-427; 62756-429; 0054-0479; 42571-275; 51927-5030; 12817-054; 54382-125; 62756-038; 63190-0530; 51407-246; 65862-917; 65372-1157; 65862-863; 62991-3143; 67877-444; 10144-427; 0378-0509
Synonyms 4-Aminopyridine | 4 Aminopyridine | Dalfampridine | Pymadine | VMI-103 | VMI 103 | VMI103 | 4-Aminopyridine Sustained Release | 4 Aminopyridine Sustained Release | Sustained Release, 4-Aminopyridine | Fampridine-SR | Fampridine SR
Chemical Information
Molecular Formula C5H6N2
CAS Registry Number 504-24-5
SMILES C1=CN=CC=C1N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood pressure systolic increased13.14.03.0060.002614%Not Available
Blood sodium decreased13.11.01.0120.003921%Not Available
Blood thyroid stimulating hormone abnormal13.10.03.0050.005229%Not Available
Blood thyroid stimulating hormone decreased13.10.03.0110.010457%Not Available
Blood thyroid stimulating hormone increased13.10.03.0060.003921%
Blood triglycerides increased13.12.03.0010.003921%Not Available
Blood urea increased13.13.01.0060.006536%Not Available
Body temperature increased13.15.01.0010.005229%Not Available
Bone disorder15.02.04.004--Not Available
Breast cancer16.10.01.001; 21.05.01.0030.007843%Not Available
Breast pain21.05.05.0030.003921%
Breast swelling21.05.05.0080.002614%Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Burning sensation17.02.06.001; 08.01.09.0290.031372%Not Available
C-reactive protein increased13.09.01.0070.006536%Not Available
Calculus urinary20.04.02.0010.003921%Not Available
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002--Not Available
Carpal tunnel syndrome17.09.02.0010.003921%Not Available
Cataract06.06.01.001--
CD4 lymphocytes decreased13.01.06.0160.009150%
Cellulitis23.09.01.001; 11.02.01.0010.022222%Not Available
Cerebral atrophy17.11.01.0010.005229%Not Available
Cerebral haemorrhage17.08.01.003; 24.07.04.001--Not Available
Cerebral thrombosis24.01.04.003; 17.08.01.0060.002614%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Cervical dysplasia21.06.01.0020.002614%Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chest X-ray abnormal13.19.02.0010.002614%Not Available
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