Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
IIIrd nerve paralysis06.05.02.011; 17.04.02.0030.000245%Not Available
Ileus07.13.01.0010.006116%
Inguinal hernia07.16.02.0010.001223%Not Available
Injection site haemorrhage12.07.03.005; 24.07.01.010; 08.02.03.0050.000612%Not Available
Intestinal infarction07.15.02.006; 24.04.08.0080.001101%Not Available
Intestinal ischaemia24.04.08.001; 07.15.02.0010.006899%Not Available
Intestinal obstruction07.13.01.0020.006361%Not Available
Intestinal perforation07.04.06.0020.004037%Not Available
Intestinal ulcer07.04.06.0030.000612%Not Available
Intracranial aneurysm24.02.04.001; 17.08.06.0010.000489%Not Available
Intracranial pressure increased17.07.02.0020.001468%Not Available
Intraventricular haemorrhage24.07.04.008; 17.08.01.0170.003792%Not Available
Iron deficiency14.13.02.0020.000612%Not Available
Iron deficiency anaemia14.13.02.001; 01.03.01.0020.003841%Not Available
Joint effusion15.01.02.0050.000367%
Large intestinal ulcer07.04.06.0040.000245%
Large intestine perforation12.02.03.005; 07.04.06.0050.002080%
Left ventricular failure02.05.02.0010.000367%Not Available
Lung consolidation22.01.02.0100.000367%Not Available
Lymphoma16.20.01.001; 01.12.01.0010.001468%Not Available
Mallory-Weiss syndrome07.12.01.004; 24.07.02.0380.000979%Not Available
Megacolon07.02.05.0020.000245%Not Available
Melaena24.07.02.013; 07.12.02.0040.041102%Not Available
Mesenteric artery thrombosis24.01.08.003; 07.15.02.0080.000612%Not Available
Metastatic malignant melanoma23.08.01.002; 16.03.01.0020.000367%Not Available
Microcytic anaemia01.03.02.0080.001101%Not Available
Mitral valve incompetence02.07.01.0020.001884%Not Available
Monoparesis17.01.04.0110.001713%Not Available
Monoplegia17.01.04.0030.000979%Not Available
Mouth haemorrhage24.07.02.014; 07.05.02.0010.004306%
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