Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Haemorrhagic disorder24.07.01.021; 01.01.03.0040.001223%Not Available
Haemorrhagic stroke24.07.04.014; 17.08.01.0110.017371%Not Available
Haemorrhoids24.10.02.002; 07.15.03.0010.006753%
Haemothorax12.01.18.005; 24.07.01.008; 22.05.02.0010.007951%
Hemianopia06.02.07.004; 17.17.01.0120.000856%Not Available
Hemiparesis17.01.04.0010.018472%
Hemiplegia17.01.04.0020.009664%Not Available
Hepatic cyst09.01.08.008; 16.06.02.0010.000245%Not Available
Hepatic failure09.01.03.0020.005382%
Hepatic haemorrhage12.01.17.009; 24.07.01.027; 09.01.06.0080.001101%
Hepatic neoplasm16.07.03.001; 09.04.03.0010.000367%Not Available
Hepatitis09.01.07.0040.003156%Not Available
Hepatitis acute09.01.07.0050.001101%Not Available
Hepatitis cholestatic09.01.01.0020.000979%Not Available
Hepatorenal syndrome09.01.03.007; 20.01.03.0120.000612%Not Available
Hiatus hernia22.09.02.004; 07.16.01.0010.000979%Not Available
Hydrocephalus17.07.01.0010.001468%
Hydronephrosis20.01.05.0010.000856%Not Available
Hypercapnia22.02.02.002; 14.01.04.0010.000367%Not Available
Hypercoagulation01.01.02.0070.001272%Not Available
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis24.12.04.013; 23.06.02.005; 10.02.02.017; 01.01.04.0080.000734%Not Available
Hypertensive crisis24.08.01.0010.002691%Not Available
Hypochloraemia14.05.08.0030.000245%Not Available
Hypochromic anaemia01.03.02.0040.000367%Not Available
Hypocoagulable state01.01.02.0040.001957%Not Available
Hypoprothrombinaemia01.01.01.0010.000489%Not Available
Hypotension24.06.03.002--
Hypovolaemia14.05.05.0020.001957%Not Available
Hypovolaemic shock24.06.02.0170.008196%Not Available
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