Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cyproterone acetate
Drug ID BADD_D00555
Description An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Indications and Usage For the palliative treatment of patients with advanced prostatic carcinoma.
Marketing Status Not Available
ATC Code G03HA01
DrugBank ID DB04839
KEGG ID D01368
MeSH ID D017373
PubChem ID 9880
TTD Drug ID Not Available
NDC Product Code 59010-000; 46439-8720; 53104-7635
Synonyms Cyproterone Acetate | Cyproterone Acetate, (17 alpha)-Isomer | Cyproterone Acetate, (1 alpha,2 alpha,9 beta,10 alpha)-Isomer | Androcur | Cyproterone Acetate, (1 alpha,2 alpha)-Isomer
Chemical Information
Molecular Formula C24H29ClO4
CAS Registry Number 427-51-0
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)OC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hepatic failure09.01.03.002--
Hepatic necrosis09.01.07.002--
Hepatic neoplasm16.07.03.001; 09.04.03.001--Not Available
Hepatitis09.01.07.004--Not Available
Hepatomegaly09.01.05.001--Not Available
Hernia08.01.04.001--Not Available
Hirsutism05.05.01.005; 23.02.04.001--
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypernatraemia14.05.04.001--
Hypersensitivity10.01.03.003--
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypochromic anaemia01.03.02.004--Not Available
Hypotension24.06.03.002--
Immune system disorder10.02.01.001--Not Available
Infertility21.03.02.001--Not Available
Injection site reaction08.02.03.014; 12.07.03.015--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukocytosis01.02.01.002--
Leukopenia01.02.02.001--Not Available
Libido decreased19.08.03.001; 21.03.02.005--
Libido increased21.03.02.007; 19.08.03.002--
Liver function test abnormal13.03.01.013--Not Available
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Meningioma17.20.01.005; 16.30.01.005--Not Available
Menopausal symptoms21.02.02.002--Not Available
Menstruation irregular21.01.01.005; 05.05.01.008--
The 3th Page    First    Pre   3 4 5 6    Next   Last    Total 6 Pages