Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cyproterone
Drug ID BADD_D00554
Description An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Indications and Usage For the palliative treatment of patients with advanced prostatic carcinoma.
Marketing Status Not Available
ATC Code G03HA01
DrugBank ID DB04839
KEGG ID D07766
MeSH ID D003534
PubChem ID 5284537
TTD Drug ID D06AEO
NDC Product Code 53104-7635; 46439-8720; 59010-000
Synonyms Cyproterone | Cyproterone, 1alpha,2 alpha,9 beta,10 alpha-Isomer
Chemical Information
Molecular Formula C22H27ClO3
CAS Registry Number 2098-66-0
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Optic atrophy06.09.02.001--Not Available
Optic neuritis06.04.08.002; 17.04.05.001; 10.04.10.002--Not Available
Osteoporosis15.02.03.002; 14.04.04.002--
Pain08.01.08.004--
Pancreatitis07.18.01.001--
Phlebitis24.05.03.001; 12.02.01.002--
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Pulmonary fibrosis22.01.02.006--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Retinal vascular disorder24.03.07.002; 06.10.01.002--
Retinal vein thrombosis24.01.07.002; 06.10.01.003--Not Available
Shock24.06.02.002--Not Available
Skin discolouration23.03.03.005--Not Available
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.003--Not Available
Spermatozoa abnormal13.20.01.005--Not Available
Syncope17.02.04.008; 02.01.02.008; 24.06.02.012--
Tachycardia02.03.02.007--Not Available
Tenderness08.01.08.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombosis24.01.01.006--Not Available
Vascular headache24.03.05.007; 17.14.01.005--Not Available
Vomiting07.01.07.003--
Weight increased13.15.01.006--
Nodular regenerative hyperplasia09.01.04.004--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
The 3th Page    First    Pre   3 4    Next   Last    Total 4 Pages