Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cycloserine
Drug ID BADD_D00550
Description Antibiotic substance produced by Streptomyces garyphalus.
Indications and Usage Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Marketing Status Prescription
ATC Code J04AB01
DrugBank ID DB00260
KEGG ID D00877
MeSH ID D003523
PubChem ID 6234
TTD Drug ID D02WFK
NDC Product Code 13845-1203; 13845-1201; 72643-027; 13845-1202; 13845-1200
Synonyms Cycloserine | R-4-Amino-3-isoxazolidinone | Seromycin
Chemical Information
Molecular Formula C3H6N2O2
CAS Registry Number 68-41-7
SMILES C1C(C(=O)NO1)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aggression19.05.01.001--Not Available
Amnesia19.20.01.001; 17.03.02.001--
Cardiac failure congestive02.05.01.002--Not Available
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Dermatitis23.03.04.002--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Drug hypersensitivity10.01.01.001--Not Available
Dysarthria19.19.03.001; 17.02.08.001--
Feeling abnormal08.01.09.014--Not Available
Headache17.14.01.001--
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Irritability19.04.02.013; 08.01.03.011--
Osteoarthritis15.01.04.001--Not Available
Paraesthesia17.02.06.005--
Paresis17.01.04.008--Not Available
Personality change19.05.01.006; 17.02.05.019--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Tremor17.01.06.002--
Vertigo04.04.01.003; 17.02.12.002--
Clonic convulsion17.12.03.008--Not Available
Transaminases increased13.03.01.015--Not Available
Hypertensive nephropathy24.08.05.003; 20.01.08.004--Not Available
Neurological symptom17.02.05.010--Not Available
Psychotic disorder19.03.01.002--
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