| Pharmaceutical Information |
| Drug Name |
Cyanocobalamin |
| Drug ID |
BADD_D00542 |
| Description |
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms. The _cyano_ form, is the most widely used form in supplements and prescription drugs [A175255], [FDA label]. Several pharmaceutical forms of cyanocobalamin have been developed, including the tablet, injection, and nasal spray forms [FDA label], [L5542], [L5545]. This drug was initially approved by the FDA in 1942 [FDA label]. |
| Indications and Usage |
For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin B 12 deficiency. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
B03BA01 |
| DrugBank ID |
DB00115
|
| KEGG ID |
D00166
|
| MeSH ID |
D014805
|
| PubChem ID |
5311498
|
| TTD Drug ID |
D0FR6I
|
| NDC Product Code |
70069-172; 69680-113; 76420-111; 52584-399; 70529-293; 0143-9621; 72843-497; 0404-9840; 70069-171; 50396-7800; 70529-290; 40074-0013; 0517-0130; 63323-044; 76420-075; 70069-005; 72843-507; 50090-2709; 0143-9619; 68001-509; 63238-3700; 0517-0031; 69680-112; 55150-364; 51662-1394; 16729-533; 51927-1662; 0143-9620; 69680-121; 0517-0032; 49884-270; 0395-8140; 51662-1440; 68083-449; 81376-303; 82298-201; 51552-1045; 72843-487 |
| Synonyms |
Vitamin B 12 | B 12, Vitamin | Vitamin B12 | B12, Vitamin | Cyanocobalamin | Cobalamins | Cobalamin | Eritron |
|
| Chemical Information |
| Molecular Formula |
C63H88CoN14O14P |
| CAS Registry Number |
68-19-9 |
| SMILES |
CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=
C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC
(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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