Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cortisone
Drug ID BADD_D00532
Description A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Indications and Usage Not Available
Marketing Status experimental
ATC Code H02AB10; S01BA03
DrugBank ID DB14681
KEGG ID D07749
MeSH ID D003348
PubChem ID 222786
TTD Drug ID D0IX6I
NDC Product Code Not Available
UNII V27W9254FZ
Synonyms Cortisone | Cortisone Acetate | 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate | Cortone Acetate | Adreson
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 53-06-5
SMILES CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Intraocular pressure increased13.07.04.002--Not Available
Malaise08.01.01.003--
Mass08.03.05.003--Not Available
Menstruation irregular21.01.01.005; 05.05.01.008--
Muscular weakness17.05.03.005; 15.05.06.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial rupture12.01.11.002; 02.04.02.002--Not Available
Myopathy15.05.05.001--Not Available
Nausea07.01.07.001--
Nitrogen balance negative13.13.01.010--Not Available
Optic neuritis10.02.01.097; 17.04.05.001; 06.04.08.002--Not Available
Osteonecrosis15.02.04.007; 24.04.05.004--
Osteoporosis15.02.03.002; 14.04.04.002--
Pancreatitis07.18.01.001--
Papilloedema24.03.07.001; 17.07.02.004; 06.09.02.002--
Peptic ulcer07.04.07.001--Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Seizure17.12.03.001--
Spinal compression fracture15.08.05.004; 14.04.04.003; 12.04.04.001--Not Available
Tendon rupture12.01.07.003; 15.07.01.008--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Weight increased13.15.01.006--
Oesophagitis ulcerative07.04.05.003--Not Available
Acute coronary syndrome02.02.02.015; 24.04.04.011--Not Available
Haemorrhage24.07.01.002--Not Available
Muscle mass15.05.03.018--Not Available
Embolism24.01.01.009--
Ill-defined disorder08.01.03.049--Not Available
Idiopathic intracranial hypertension17.07.02.011--Not Available
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