| Pharmaceutical Information |
| Drug Name |
Colchicine |
| Drug ID |
BADD_D00518 |
| Description |
First approved by the FDA in 1961, colchicine is an alkaloid drug commonly used in the management of gout, a condition associated with the painful deposition of urate crystals in the joints.[A183614,L8138] It is derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus".[A183611] Other than its use in gout, colchicine has been approved for managing exacerbations of Familial Mediterranean Fever (FMF), a hereditary autoinflammatory condition.[A186320,L8141] |
| Indications and Usage |
For treatment and relief of pain in attacks of acute gouty arthritis. |
| Marketing Status |
Prescription |
| ATC Code |
M04AC01 |
| DrugBank ID |
DB01394
|
| KEGG ID |
D00570
|
| MeSH ID |
D003078
|
| PubChem ID |
6167
|
| TTD Drug ID |
D09DHY
|
| NDC Product Code |
75854-801; 0378-1086; 0591-2562; 68071-2567; 55742-127; 49452-2210; 43353-854; 43598-372; 63629-2167; 63629-8362; 70710-1351; 50268-187; 66064-1008; 59651-455; 59467-318; 64764-119; 31722-899; 63187-292; 65162-710; 72189-331; 72189-249; 63629-7422; 47234-0119; 0254-2008; 17359-5000; 0143-3018; 0904-7120; 16714-039; 63629-2166; 63629-8766; 70771-1590; 0904-6732; 61281-3600; 69037-0011; 71205-310; 71335-1802; 71610-494; 51927-1895; 68404-0001; 67296-1708; 60687-358; 72643-009; 70771-1396; 67877-589; 51407-082; 42292-054; 70010-002; 71335-1695; 70710-1571; 71335-1738; 60687-389 |
| Synonyms |
Colchicine | Colchicine, (R)-Isomer | Colchicine, (+-)-Isomer |
|
| Chemical Information |
| Molecular Formula |
C22H25NO6 |
| CAS Registry Number |
64-86-8 |
| SMILES |
CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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