Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clopidogrel
Drug ID BADD_D00504
Description Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin.[A180547] Clopidogrel was granted FDA approval on 17 November 1997.[L7213]
Indications and Usage Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease,[L7213]
Marketing Status approved
ATC Code B01AC04
DrugBank ID DB00758
KEGG ID D07729; D10823; D10824
MeSH ID D000077144
PubChem ID 60606
TTD Drug ID D0N0TZ
NDC Product Code 42543-714; 50090-4918; 52605-083; 16729-218; 0024-1171; 68788-8190; 72578-012; 65977-0037; 52605-082; 63187-362; 63629-4728; 70518-0400; 33342-060; 42543-713; 65162-414; 0093-7314; 16729-219; 61919-007; 67296-1840; 50090-2598; 50090-5781; 0024-1332; 61919-737; 70771-1062; 16714-052; 68071-2813; 68071-4138; 71335-0581
UNII A74586SNO7
Synonyms Clopidogrel | SC 25989C | SC 25990C | SR 25989 | Clopidogrel-Mepha | Clopidogrel Mepha | Clopidogrel Sandoz | Iscover | Clopidogrel Napadisilate | Clopidogrel Hydrochloride | PCR 4099 | PCR-4099 | Clopidogrel Besylate | Clopidogrel Besilate | Clopidogrel, (+)(S)-isomer | Plavix | Clopidogrel Bisulfate
Chemical Information
Molecular Formula C16H16ClNO2S
CAS Registry Number 113665-84-2
SMILES COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Autonomic neuropathy17.05.01.009--Not Available
Disease recurrence08.01.03.050--Not Available
Obstructive airways disorder22.03.01.0110.000021%Not Available
Hepatobiliary disease09.01.08.003--Not Available
Renal impairment20.01.03.0100.000513%Not Available
Heparin-induced thrombocytopenia24.01.01.020; 10.02.01.007; 01.08.01.0040.000086%Not Available
Poor quality sleep17.15.04.002; 19.02.05.0050.000068%Not Available
Peripheral arterial occlusive disease24.04.03.0100.000096%Not Available
Arterial occlusive disease24.04.02.0210.000064%Not Available
Haemorrhagic diathesis24.07.01.020; 01.01.03.0030.000086%Not Available
Cystitis noninfective20.03.02.001--
Erosive oesophagitis07.04.05.0040.000064%Not Available
Vascular stent thrombosis24.01.01.044; 08.07.05.0020.000610%Not Available
Gastrointestinal inflammation07.08.03.0070.000021%Not Available
Skin haemorrhage24.07.01.103; 23.06.07.0010.000079%Not Available
Exfoliative rash23.03.07.006--Not Available
Spontaneous haematoma24.07.01.054; 01.01.03.0060.000096%Not Available
Infusion site haemorrhage08.02.05.018; 24.07.01.058; 12.07.05.0180.000021%Not Available
Nephritic syndrome20.05.01.006--Not Available
Bronchial haemorrhage24.07.01.045; 22.03.02.0070.000021%Not Available
Vessel puncture site haematoma24.07.01.018; 12.07.04.003; 08.02.04.0020.000032%Not Available
Transfusion25.06.01.003--Not Available
Haematological malignancy16.21.01.002; 01.13.01.0030.000032%Not Available
Liver injury09.01.07.022; 12.01.17.012--Not Available
Regurgitation07.01.07.0040.000021%Not Available
Pharyngeal disorder22.04.05.007--Not Available
Organising pneumonia22.01.02.0080.000021%Not Available
Haemorrhagic erosive gastritis24.07.02.037; 07.04.03.0080.000021%Not Available
Brain injury19.07.03.007; 17.11.01.0030.000043%Not Available
Traumatic liver injury09.01.08.010; 12.01.17.027--Not Available
The 22th Page    First    Pre   22 23 24 25 26    Next   Last    Total 27 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene