| Drug Name |
Clonazepam |
| Drug ID |
BADD_D00501 |
| Description |
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop [FDA Label] [L5572, F3763, F3787, F3796]. The agent has also been indicated for treating panic disorder [FDA Label] [A175438, L5572, F3763, F3787, F3796]. The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses [FDA Label] [A175438, A175441, L5572, F3763, F3787, F3796].
Since being first patented in 1960 and then released for sale from Roche in the US in 1975 [T469, T472], clonazepam has experienced a storied history in the treatment of the aforementioned medical conditions. Now available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year. Unfortunately, however, like most benzodiazepines, clonazepam use has also been associated with recreational use and drug abuse [FDA Label] [L5572, F3763, F3787, F3796]. |
| Indications and Usage |
Clonazepam is used as an anticonvulsant in the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures. It can also be used for the treatment of panic disorders. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N03AE01 |
| DrugBank ID |
DB01068
|
| KEGG ID |
D00280
|
| MeSH ID |
D002998
|
| PubChem ID |
2802
|
| TTD Drug ID |
D0CP4E
|
| NDC Product Code |
57664-784; 43063-794; 17856-0834; 0228-3004; 62756-110; 0093-9290; 60429-525; 71335-1843; 63629-8988; 70518-1297; 70518-2334; 51552-1567; 68071-5163; 62332-368; 60687-555; 80425-0125; 0615-8235; 68788-7181; 50090-4299; 60760-273; 68788-7394; 49884-308; 0004-0058; 49884-310; 63629-1207; 68071-4135; 55154-6831; 62332-364; 70518-1521; 71610-084; 43353-308; 71610-366; 43547-408; 57664-785; 61919-485; 51407-524; 80425-0135; 63629-1203; 50090-4842; 0615-8234; 12828-0060; 58118-0832; 46708-367; 61919-058; 55700-564; 46708-368; 57664-787; 48087-0038; 53002-7451; 51927-4663; 50090-2022; 71335-0022; 70518-2485; 71610-061; 67544-529; 45865-575; 71610-367; 62332-367; 63187-603; 62332-365; 49884-309; 70518-3144; 0004-0068; 68071-2310; 46708-366; 60687-544; 67544-288; 0093-9291; 72189-081; 71610-040; 50090-3467; 70518-1353; 49884-306; 50090-2088; 16729-137; 71335-0113; 68788-7738; 0093-3213; 70518-1801; 63629-8226; 71205-529; 43353-307; 43063-797; 71610-390; 61269-605; 60429-526; 63629-1202; 63187-888; 43547-406; 62332-366; 48087-0014; 63629-1205; 71610-085; 16729-138; 0395-8179; 68071-4021; 68071-5247; 55154-8125; 70518-2467; 0004-0098; 71610-363; 60429-524; 55700-830; 0228-3003; 63187-226; 0093-9294; 70518-2232; 49884-307; 0093-3212; 71610-039; 70518-1559; 61269-610; 43063-788; 71205-252; 71610-075; 67544-412; 71554-021; 0615-8236; 63629-1206; 70518-2507; 61269-620; 16729-136; 0093-9293; 71335-0333; 63629-1201; 63629-7649; 70518-2392; 63629-1116; 71335-1810; 71610-023; 71335-1856; 71610-368; 57664-783; 43547-407; 70518-2533; 64330-019; 57664-786; 50090-5399; 63629-1204; 0093-9292; 0093-0832; 46708-364; 67544-256; 46708-365; 17856-0835 |
| Synonyms |
Clonazepam | 2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro- | Rivotril | Klonopin | Antelepsin | Ro 5-4023 | Ro 54023 |
