Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
UNII 1HRS458QU2
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hot flush21.02.02.001; 08.01.03.027; 24.03.01.005--
Abdominal symptom07.01.06.007--Not Available
Embolism24.01.01.009--
Gastrointestinal malformation07.11.04.004; 03.04.07.002--Not Available
Psychotic disorder19.03.01.002--
Hepatoblastoma16.07.04.001; 09.04.02.003--Not Available
Arterial occlusive disease24.04.02.021--Not Available
Pelvic discomfort21.10.01.012; 20.02.03.012; 07.01.06.020--Not Available
Tibial torsion15.11.07.009; 03.11.07.009--Not Available
Renal aplasia20.01.02.001; 03.06.01.002--Not Available
Ovarian haemorrhage24.07.03.009; 21.11.02.006--
Hepatic angiosarcoma24.03.06.007; 16.07.02.003; 09.04.02.007--Not Available
Cloacal exstrophy21.15.02.003; 20.08.03.004; 07.11.04.005; 03.03.02.004--Not Available
Cytogenetic abnormality03.20.02.002--Not Available
Renal cell carcinoma20.01.04.003; 16.08.02.002--Not Available
Intellectual disability19.21.06.001; 17.03.07.001--Not Available
Adnexal torsion21.11.02.012--Not Available
Hepatic cancer16.07.02.004; 09.04.02.008--Not Available
Hepatocellular carcinoma16.07.02.005; 09.04.02.010--Not Available
Prolactin-producing pituitary tumour16.24.07.001; 05.03.05.005--Not Available
Congenital musculoskeletal disorder of skull15.11.02.011; 03.11.02.011--Not Available
Haemoperitoneum24.07.02.065; 12.01.17.007; 07.07.02.007--Not Available
Heavy menstrual bleeding21.01.03.005--Not Available
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