| ADR Ontology |
| ADR Term |
Cytogenetic abnormality |
| ADR ID |
BADD_A06440 |
| ADR Hierarchy |
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| Description |
Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS. [MeSH] |
| MedDRA Code |
10067477 |
| MeSH ID |
D002869; D002869; D002869; D002869; D025063
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Chromosomal abnormality in fetus affecting management of mother | Chromosomal abnormality in fetus, affecting manag of mother, unspec as to eoc in preg | Chromosomal abnormality in fetus, affecting management of mother, antepartum | Chromosomal abnormality in fetus, affecting management of mother, with delivery | Chromosomal abnormality NOS | Chromosomal anomalies | Chromosome abnormality | Chromosome disorder | Conditions due to anomaly of unspecified chromosome | Cytogenetic abnormality | Chromosome Aberrations | Aberration, Chromosome | Aberrations, Chromosome | Chromosome Aberration | Abnormalities, Chromosome | Abnormality, Chromosome | Chromosome Abnormality | Cytogenetic Abnormalities | Abnormalities, Cytogenetic | Abnormality, Cytogenetic | Cytogenetic Abnormality | Chromosome Abnormalities | Cytogenetic Aberrations | Aberration, Cytogenetic | Aberrations, Cytogenetic | Cytogenetic Aberration | Abnormalities, Chromosomal | Abnormality, Chromosomal | Chromosomal Abnormalities | Chromosomal Abnormality | Chromosomal Aberrations | Aberration, Chromosomal | Aberrations, Chromosomal | Chromosomal Aberration | Autosome Abnormalities | Abnormality, Autosome | Autosome Abnormality | Abnormalities, Autosome |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| 5-hydroxytryptamine receptor 1F | P30939 | T78656 | | Calcitonin gene-related peptide 1 | P06881 | T93509 | | Cellular tumor antigen p53 | P04637 | T15739 | | Cyclin-dependent kinase 20 | Q8IZL9 | Not Available | | DNA topoisomerase 2-alpha | P11388 | T17048 | | DNA-directed RNA polymerase, mitochondrial | O00411 | Not Available | | Glucose-6-phosphate 1-dehydrogenase | P11413 | T63484 | | Hypoxanthine-guanine phosphoribosyltransferase | P00492 | Not Available | | L-lactate dehydrogenase A chain | P00338 | T15053 | | Mitogen-activated protein kinase 1 | P28482 | T58970 | | Poly(A) polymerase alpha | P25500 | Not Available | | RAF proto-oncogene serine/threonine-protein kinase | P09560 | Not Available | | Retinoblastoma tumor suppressor | Q5J3Q9 | Not Available | | Serine/threonine-protein kinase PLK2 | Q9NYY3 | T59654 |
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| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D00483 | Clindamycin | - | - | | BADD_D00486 | Clindamycin palmitate hydrochloride (pediatric) | - | - | | BADD_D00497 | Clomiphene | - | - | | BADD_D02043 | Sodium iodide i-131 | - | - |
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