Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status Prescription; Discontinued
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cleft lip07.05.08.002; 03.11.05.002; 15.11.05.002--Not Available
Cleft palate07.05.08.001; 03.04.02.001--Not Available
Coarctation of the aorta24.04.01.002; 03.07.08.001--Not Available
Congenital anomaly03.02.01.001--Not Available
Congenital central nervous system anomaly17.19.01.003; 03.10.02.004--Not Available
Conjoined twins18.03.02.010; 03.02.01.009--Not Available
Constipation07.02.02.001--
Cryptorchism21.15.01.001; 05.05.02.002; 03.03.01.001--Not Available
Cyst16.02.02.002; 08.03.05.001--Not Available
Deafness04.02.01.001--Not Available
Death neonatal08.04.01.002; 18.04.01.002--
Dependence19.07.02.003--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis atopic23.03.04.016; 10.01.04.004--Not Available
Dermoid cyst16.02.02.006; 03.05.01.005--Not Available
Developmental delay08.01.03.037--Not Available
Diaphragmatic hernia22.09.02.001; 07.16.01.002--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug abuse19.07.02.010--Not Available
Dwarfism15.02.03.005; 05.03.02.002--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Ectopic pregnancy18.02.02.002--Not Available
Endometrial cancer21.07.02.002; 16.12.02.001--Not Available
Endometriosis21.07.01.004--Not Available
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Exomphalos07.16.03.002; 03.04.07.001--Not Available
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